High dose dexamethasone treatment for Acute Respiratory Distress Syndrome secondary to COVID-19: a structured summary of a study protocol for a randomised …

LP Maskin, GL Olarte, F Palizas, AE Velo, MF Lurbet… - Trials, 2020 - Springer
Objectives The aim of this study is to explore the effectiveness and safety of high dose
dexamethasone treatment for Acute Respiratory Distress Syndrome secondary to SARS-Cov …

No clinical benefit of high dose corticosteroid administration in patients with COVID-19: a preliminary report of a randomized clinical trial

H Jamaati, SMR Hashemian, B Farzanegan… - European journal of …, 2021 - Elsevier
The aim of this study was to evaluate the clinical effects of dexamethasone administration in
patients with mild to moderate acute respiratory distress syndrome (ARDS) due to …

Dexamethasone in hospitalized patients with Covid-19-preliminary report

L Chappell, P Horby, WS Lim… - The New England …, 2020 - kclpure.kcl.ac.uk
Background: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage.
Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce …

[HTML][HTML] Comparison of the effect of intravenous dexamethasone and methylprednisolone on the treatment of hospitalized patients with COVID-19: a randomized …

ZH Dastenae, A Bahadori, M Dehghani… - International Journal of …, 2022 - Elsevier
Objective In this study, we aimed to compare the effects of intravenous dexamethasone and
methylprednisolone on the treatment of inpatients with COVID-19. Methods In this …

[PDF][PDF] Short-term dexamethasone in Sars-CoV-2 patients

V Selvaraj, K Dapaah-Afriyie, A Finn, TP Flanigan - RI Med J, 2020 - rimed.org
ABSTRACT BACKGROUND: Dexamethasone, a synthetic glucocorticoid, has anti-
inflammatory and immunosuppressive properties. There is a hyperinflammatory response …

Role of dexamethasone and methylprednisolone corticosteroids in coronavirus disease 2019 hospitalized patients: a review

J Mehta, R Rolta, BB Mehta, N Kaushik… - Frontiers in …, 2022 - frontiersin.org
The WHO announced coronavirus disease 2019 (COVID-19) as a pandemic disease
globally on March 11, 2020, after it emerged in China. The emergence of COVID-19 has …

[PDF][PDF] Dexamethasone for COVID-19? Not so fast

TC Theoharides, P Conti - J Biol Regul Homeost Agents, 2020 - researchgate.net
Recent announcements indicated, without sharing any distinct published set of results, that
use of the corticosteroid dexamethasone in a large trial in the UK apparently reduced …

Outcomes of patients with severe and critical COVID-19 treated with dexamethasone: a prospective cohort study

BA Martinez-Guerra, MF Gonzalez-Lara… - Emerging Microbes & …, 2022 - Taylor & Francis
Dexamethasone implementation for COVID-19 management represented a milestone but
data regarding its impact and safety have not been consistently reproduced. We aimed to …

Potential health and economic impacts of dexamethasone treatment for patients with COVID-19

R Águas, A Mahdi, R Shretta, P Horby… - Nature …, 2021 - nature.com
Dexamethasone can reduce mortality in hospitalised COVID-19 patients needing oxygen
and ventilation by 18% and 36%, respectively. Here, we estimate the potential number of …

The use of dexamethasone in the treatment of COVID-19

M Lester, A Sahin, A Pasyar - Annals of Medicine and Surgery, 2020 - journals.lww.com
After reading around regarding the state of knowledge surrounding the COVID-19 outbreak,
we were intrigued by the lack of a general consensus on what constituted effective anti-viral …