Effectiveness of COVID‑19 vaccines and their challenges

G Marfe, S Perna, AK Shukla - Experimental and …, 2021 - spandidos-publications.com
At the end of 2019, a new disease recognized such as severe acute respiratory syndrome
(SARS), was reported in Wuhan, China. This disease was caused by an unknown SARS …

COVID-19 vaccines: current understanding on immunogenicity, safety, and further considerations

Q He, Q Mao, J Zhang, L Bian, F Gao, J Wang… - Frontiers in …, 2021 - frontiersin.org
The world has entered the second wave of the COVID-19 pandemic, and its intensity is
significantly higher than that of the first wave of early 2020. Many countries or regions have …

Vaccines for COVID-19

JS Tregoning, ES Brown… - Clinical & …, 2020 - academic.oup.com
Since the emergence of COVID-19, caused by the SARS-CoV-2 virus at the end of 2019,
there has been an explosion of vaccine development. By 24 September 2020, a staggering …

Postlicensure evaluation of COVID-19 vaccines

MM Patel, ML Jackson, J Ferdinands - JAMA, 2020 - jamanetwork.com
After rigorous clinical trialsof vaccines for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have established safety and efficacy, and after vaccines are deployed …

Avoiding pitfalls in the pursuit of a COVID-19 vaccine

L Peeples - Proceedings of the national academy of …, 2020 - National Acad Sciences
The teams of researchers scrambling to develop a coronavirus disease 2019 (COVID-19)
vaccine clearly face some big challenges, both scientific and logistical. One of the most …

Viral targets for vaccines against COVID-19

L Dai, GF Gao - Nature Reviews Immunology, 2021 - nature.com
Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19)
pandemic and to help the return to pre-pandemic normalcy. A great many vaccine …

[HTML][HTML] COVID‐19: Current knowledge in clinical features, immunological responses, and vaccine development

R Singh, A Kang, X Luo, M Jeyanathan… - The FASEB …, 2021 - ncbi.nlm.nih.gov
The COVID‐19 pandemic has unfolded to be the most challenging global health crisis in a
century. In 11 months since its first emergence, according to WHO, the causative infectious …

Consensus summary report for CEPI/BC March 12–13, 2020 meeting: assessment of risk of disease enhancement with COVID-19 vaccines

PH Lambert, DM Ambrosino, SR Andersen, RS Baric… - Vaccine, 2020 - Elsevier
A novel coronavirus (CoV), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), emerged in late 2019 in Wuhan, China and has since spread as a global pandemic. Safe …

[HTML][HTML] Evaluating and deploying COVID-19 vaccines—The importance of transparency, scientific integrity, and public trust

JL Schwartz - New England Journal of Medicine, 2020 - Mass Medical Soc
Evaluating and Deploying Covid-19 Vaccines New entities and investments have aided the
pursuit of Covid-19 vaccines. Moving forward, relying on time-tested mechanisms for …

Looking beyond COVID-19 vaccine phase 3 trials

JH Kim, F Marks, JD Clemens - Nature medicine, 2021 - nature.com
After the recent announcement of COVID-19 vaccine efficacy in clinical trials by several
manufacturers for protection against severe disease, a comprehensive post-efficacy strategy …