Diagnosis of SARS-CoV-2 by RT-PCR using different sample sources: review of the literature

S Torretta, G Zuccotti, V Cristofaro… - Ear, Nose & Throat …, 2021 - journals.sagepub.com
Objective: The most widely used diagnostic technique for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is real-time reverse transcriptase-polymerase chain …

Does sampling saliva increase detection of SARS-CoV-2 by RT-PCR? Comparing saliva with oro-nasopharyngeal swabs

OA Dogan, B Kose, NB Agaoglu, J Yildiz… - Journal of Virological …, 2021 - Elsevier
The gold standard method in the diagnosis of SARS-CoV-2 infection is the detection of viral
RNA in the nasopharyngeal sample by RT-PCR. Recently, saliva samples have been …

Detection profile of SARS‐CoV‐2 using RT‐PCR in different types of clinical specimens: a systematic review and meta‐analysis

GM Bwire, MV Majigo, BJ Njiro… - Journal of medical …, 2021 - Wiley Online Library
Testing is one of the commendable measures for curbing the spread of coronavirus disease
(COVID‐19). But, it should be done using the most appropriate specimen and an accurate …

Diagnostic accuracy of nasopharyngeal swab, nasal swab and saliva swab samples for the detection of SARS-CoV-2 using RT-PCR

Y Tsujimoto, J Terada, M Kimura, A Moriya… - Infectious …, 2021 - Taylor & Francis
Background The current gold standard in coronavirus disease (COVID-19) diagnostics is the
real-time reverse transcription–polymerase chain reaction (RT-PCR) assay for detecting …

The effect of sample site, illness duration, and the presence of pneumonia on the detection of SARS-CoV-2 by real-time reverse transcription PCR

S Sutjipto, PH Lee, JY Tay, SM Mendis… - Open Forum …, 2020 - academic.oup.com
Background The performance of real-time reverse transcription polymerase chain reaction
(rRT-PCR) for SARS-CoV-2 varies with sampling site (s), illness stage, and infection site …

Comparison of throat washings, nasopharyngeal swabs and oropharyngeal swabs for detection of SARS-CoV-2

F Hitzenbichler, S Bauernfeind, B Salzberger… - Viruses, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA is detected by
reverse-transcription quantitative real-time PCR (RT-qPCR) from respiratory specimens …

Detection of SARS-CoV-2 using qRT-PCR in saliva obtained from asymptomatic or mild COVID-19 patients, comparative analysis with matched nasopharyngeal …

K Ota, K Yanagihara, D Sasaki, N Kaku, N Uno… - PLoS …, 2021 - journals.plos.org
Objectives The accurate detection of severe acute respiratory syndrome–coronavirus 2
(SARS-CoV-2) is essential for the diagnosis of coronavirus disease 2019 (COVID-19). We …

Diagnosis of SARS-Cov-2 infection by RT-PCR using specimens other than naso-and oropharyngeal swabs: a systematic review and meta-analysis

VM Moreira, P Mascarenhas, V Machado, J Botelho… - Diagnostics, 2021 - mdpi.com
The rapid and accurate testing of SARS-CoV-2 infection is still crucial to mitigate, and
eventually halt, the spread of this disease. Currently, nasopharyngeal swab (NPS) and …

Alternative clinical specimens for the detection of SARS‐CoV‐2: a rapid review

L Comber, KA Walsh, K Jordan… - Reviews in Medical …, 2021 - Wiley Online Library
The collection of nasopharyngeal swabs to test for the presence of severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) is an invasive technique with implications for …

Saliva as a diagnostic specimen for detection of SARS-CoV-2 in suspected patients: a scoping review

O Fakheran, M Dehghannejad… - Infectious diseases of …, 2020 - mednexus.org
Background: From the begging months of 2020 a severe acute respiratory syndrome
coronavirus (SARS-CoV-2, also called 2019-nCoV) caused a devastating global outbreak …