Background COVID-19 counts 46 million people infected and killed more than 1.2 million.
Hypoxaemia is one of the main clinical manifestations, especially in severe cases. HIF1α is …

Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …

The pandemic of coronavirus disease 2019 (COVID-19) and its pathogen, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) have become the greatest current threat …

COVID-19, disease caused by the new coronavirus, SARS-CoV-2, appeared in the end of
2019 and was rapidly spread in most countries. This respiratory virus has different symptoms …

The SARS-CoV-2 virus, the pathogen causing COVID 19, has been accepted as a pandemic
by the World Health Organization. The most dreadful complication COVID 19 is hypoxemia …

The COVID-19 death toll has involved to date more than 1 million confirmed deaths. The
death rate is even higher in the obese COVID-19 patients, as a result of hypoxia, due to the …

Patients with severe COVID-19 infection exhibit a low level of oxygen in affected tissue and
blood. To understand the pathophysiology of COVID-19 infection, it is therefore necessary to …

Introduction Severe COVID-19 and non-COVID-19 pulmonary sepsis share
pathophysiological, immunological, and clinical features. To what extent they share …

Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

Background COVID19 is caused by the SARS-CoV-2 virus and has been associated with
severe inflammation leading to organ dysfunction and mortality. Our aim was to profile the …