INTRODUCTION: In 9–17% of Wilms tumour patients a predisposing syndrome is present, in
particular WT1-associated syndromes and overgrowth syndromes. Constitutional WT1 …

Purpose Constitutional WT1 mutations in patients with Wilms' tumor (WT) have specifically
been associated with genitourinary abnormalities, such as cryptorchidism and hypospadias …

OBJECTIVES: To investigate the frequency of constitutional Wilms tumor 1 gene (WT1)
abnormalities in children with bilateral Wilms tumor (WT) and the age of tumor onset in …

Study of genotype/phenotype relationships involving the Wilms' tumor (WT) gene, WT1, in
WT patients has provided insights into the function of the WT1 protein, a transcriptional …

Background: Bilateral Wilms tumours (BWTs) occur by germline mutation of various
predisposing genes; one of which is WT1 whose abnormality was reported in 17–38% of …

Purpose Children's Oncology Group defines very low-risk Wilms tumors (VLRWT) as stage I
favorable histology Wilms tumors weighing less than 550 g in children younger than 24 …

The study of Wilms tumor-predisposing congenital syndromes has led to the identification of
one tumor-suppressor gene, WT1, and to the localization of WT2. Molecular genetic …

Abstract Wilms' tumor (WT), the most common childhood kidney cancer, develops in
association with an underlying germline predisposition in up to 15% of cases. Germline …

We report here 24 new Wilms tumor (WT) patients with germline WT1 alterations and a
synopsis of our own previously described and literature cases in whom age of tumor‐onset …

Incidence rates of Wilms' tumor (WT) markedly differ in East Asian and Caucasian children.
In the present study, we examined WT1 deletions/mutations and loss of heterozygosity …