Rapid identification of bacterial pathogens is crucial for appropriate and adequate antibiotic
treatment, which significantly improves patient outcomes. 16S ribosomal RNA (rRNA) gene …

Next-generation sequencing holds potential for improving clinical and public health
microbiology. 1 In addition to identifying pathogens more rapidly and precisely than …

The escalating prevalence of multidrug-resistant (MDR) bacteria pose a significant public
health threat. Understanding the genomic features and deciphering the antibiotic resistance …

Next-generation sequencing is rapidly finding footholds in numerous microbiological fields,
including infectious disease diagnostics. Here, we describe a molecular inversion probe …

Metagenomic sequencing with the Oxford Nanopore MinION sequencer offers potential for
point-of-care testing of infectious diseases in clinical settings. To improve cost-effectiveness …

Purpose. Bloodstream infections are major causes of morbidity and mortality that lead to
prolonged hospital stays and higher medical costs. In this study, we aimed to evaluate the …

Central nervous system (CNS) infections are a leading cause of death in patients. Nanopore-
targeted sequencing (NTS) has begun to be used for pathogenic microbial detection. This …

Highlights•Rapid diagnostics are essential in the fight against antimicrobial
resistance.•BioFire® FilmArray® panels can identify pathogen resistance genes in 1 …

The convergence of several technologies such as ultrafast nanopore sequencing,
biosensors, the Internet of things (IoT), cloud computing, computational intelligence …

Enrichment of DNA by hybridisation is an important tool which enables users to gather target-
focused next-generation sequence data in an economical fashion. Current in-solution …