This is the official guideline endorsed by the specialty associations involved in the care of
head and neck cancer patients in the UK. With an age standardised incidence rate of 0.63 …

Patients with hypopharyngeal cancer are difficult to treat because they typically present with
advanced disease, poor general health status and severe nutritional problems. Currently …

Background Hypopharyngeal carcinoma is relatively rare, representing approximately 3% of
all head and neck malignancies. It also is characterized by having one of the worst …

Patients with hypopharyngeal cancers frequently present at advanced stage and in poor
general health status. Their natural history is characterised by diffuse local primary disease …

Squamous cell carcinoma of the hypopharynx represents a distinct clinical entity. Most
patients present with significant comorbidities and advanced‐stage disease. The overall …

Background: Advanced hypopharyngeal carcinoma has a dismal prognosis. The optimal
treatment for these patients remains under debate. This systematic review aimed to compare …

The optimal therapy for hypopharyngeal carcinoma depends on its staging. For early-stage
disease, radiotherapy and surgery achieve similar results. Radical surgery followed by …

This is the official guideline endorsed by the specialty associations involved in the care of
head and neck cancer patients in the UK. There has been significant debate in the …

Hypopharynx cancer has the worst prognosis of all head and neck squamous cell cancers.
Since the 1990s, a treatment shift has appeared from a total laryngectomy towards organ …

Conclusion: A significant proportion of patients with locally advanced hypopharyngeal
cancer could not be managed by larynx-sparing therapy. T4 stage is one of the main …