Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …

Cell-free DNA (cfDNA) are short DNA molecules that circulate in blood and are believed to
be derived from fragmentation of the genomic content of apoptotic and necrotic cells. cfDNA …

Cell-free DNA (cfDNA) has become widely recognized as a promising candidate biomarker
for minimally invasive characterization of various genomic disorders and other clinical …

All cell and tissue types constantly release DNA fragments into human body fluids by various
mechanisms including programmed cell death, accidental cell degradation and active …

Liquid biopsy is a broad term that refers to the testing of body fluids for biomarkers that
correlate with a pathological condition. While a variety of body-fluid components (eg …

Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …

Simple Summary Cell-free DNA—DNA that has been expelled from cells and can be
isolated from blood plasma and other body fluids—is a useful tool in medicine, with …

Cell-free DNA (cfDNA) in the circulating blood plasma of patients with cancer contains
tumour-derived DNA sequences that can serve as biomarkers for guiding therapy, for the …

An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Recent advances in basic research have unveiled several strategies for improving the
sensitivity and specificity of cell-free DNA (cfDNA) based assays, which is a prerequisite for …