AP-1 is a sequence-specific transcriptional activator composed of members of the Jun and
Fos families (for review see Ref. 1). These proteins, which belong to the bZIP group of DNA …

This issue attempts to give a 'state of the art'overview of the AP-1 transcription factor family, a
fundamental class of transcriptional regulators. The AP-1 family consists of several bZIP …

AP-1 is a collection of dimeric sequence specific, DNA binding, transcriptional activators
composed of Jun and Fos subunits. The composition, the level and the activity of AP-1 …

Activator protein-1 (AP-1) was first identified as a transcriptional factor that binds to an
essential cis-element of the human metallothionein IIA (hMTIIA) promoter [1]. AP-1 is …

Transcription factor AP-1 is inducible by phorbol esters and thus could be considered to be
one final target of the protein kinase C signal transduction pathway. AP-1 consists of the …

We describe a dominant negative (DN) to activation protein-1 (AP1) that inhibits DNA
binding in an equimolar competition. AP1 is a heterodimer of the oncogenes Fos and Jun …

Activator protein-1 (AP-1) was first identified as a transcriptional factor that binds to an
essential cis-ele-ment of the human metallothionein lla (hMTIla) promoter [1]. AP-1 is …

The role of ERK-1 and ERK-2 in wild-type (wt) Ha-Ras, phorbol 12-myristate 13-acetate
(PMA), and serum-induced AP-1 activity was studied. Microinjection of ERK-specific …

Phorbol ester tumor promoters activate gene transcription by regulating both the synthesis
and posttranslational modification of the activator protein 1 (AP-1) transcription factor, c-Jun …

The transcription factor AP-1 is activated in response to an incredible array of stimuli,
including mitogenic growth factors, inflammatory cytokines, growth factors of the TGF-β …