Background Although monotherapy for pneumococcal pneumonia is standard, a survival
benefit of combination β-lactam and macrolide therapy has been suggested. Hypothesis …

To assess the association between inclusion of a macrolide in a β-lactam—based empirical
antibiotic regimen and mortality among patients with bacteremic pneumococcal pneumonia …

Retrospective studies have suggested that combination antibiotic therapy for severe
bacteremic pneumococcal pneumonia may reduce mortality. We assessed this issue in a …

OBJECTIVE: To describe the presentation, resolution of symptoms, processes of care, and
outcomes of pneumococcal pneumonia, and to compare features of the bacteremic and …

Prospective observational study of bacteremic pneumococcal p... : Critical Care Medicine
Prospective observational study of bacteremic pneumococcal pneumonia: Effect of discordant …

Background The identification ofStreptococcus pneumoniaebacteremia in hospitalized
patients with community-acquired pneumonia is considered by some investigators to be an …

BACKGROUND: Approximately 10% of patients hospitalized with community‐acquired
pneumonia (CAP) are bacteremic. Bacteremic Streptococcus pneumoniae pneumonia …

Background: The questions of whether the use of antibiotics that are active against atypical
organisms is beneficial in the treatment of community-acquired pneumonia and of the …

We performed a prospective, international, observational study of 844 hospitalized patients
with blood cultures positive for Streptococcus pneumoniae. Fifteen percent of isolates had in …

Limited data are available about the impact of antimicrobial resistance on clinical outcomes
in cases of pneumococcal pneumonia. This was studied in 146 persons hospitalized with …