An updated systematic review of the therapeutic role of hydroxychloroquine in coronavirus disease-19 (COVID-19)

S Das, S Bhowmick, S Tiwari, S Sen - Clinical drug investigation, 2020 - Springer
Abstract Background and Objective The world is currently experiencing the Coronavirus
Disease-19 (COVID-19) pandemic. There is no approved drug for the definitive treatment of …

Role of chloroquine and hydroxychloroquine in the treatment of COVID-19 infection-a systematic literature review

KM Kapoor, A Kapoor - Medrxiv, 2020 - medrxiv.org
Background Coronavirus pandemic is currently a global public health emergency. At
present, no pharmacological treatment is known to treat this condition, and there is a need to …

[HTML][HTML] Hydroxychloroquine is effective, and consistently so when provided early, for COVID-19: a systematic review

C Prodromos, T Rumschlag - New microbes and new infections, 2020 - Elsevier
Hydroxychloroquine (HCQ) has shown efficacy against coronavirus disease 2019 (COVID-
19) in some but not all studies. We hypothesized that a systematic review would show HCQ …

Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
Background There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and
chloroquine (CQ) have been used for its treatment but their safety and efficacy remain …

[HTML][HTML] Efficacy and safety of chloroquine and hydroxychloroquine for treatment of COVID-19 patients-a systematic review and meta-analysis of randomized …

P Eze, KN Mezue, CU Nduka, I Obianyo… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 19 (COVID-19) pandemic has caused significant morbidity
and mortality worldwide and an effective treatment is needed. Chloroquine (CQ) and …

Chloroquine and Hydroxychloroquine: Efficacy in the Treatment of the COVID-19

TC Ho, YH Wang, YL Chen, WC Tsai, CH Lee… - Pathogens, 2021 - mdpi.com
Chloroquine (CQ) and its derivative, hydroxychloroquine (HCQ), have attracted wide
attention for treating coronavirus disease 2019 (COVID-19). However, conflicting outcomes …

[HTML][HTML] Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study

S Abd-Elsalam, ES Esmail, M Khalaf… - The American journal …, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is showing an exponential growth, mandating an urgent need to
develop an effective treatment. Indeed, to date, a well-established therapy is still lacking. We …

A rapid systematic review of clinical trials utilizing chloroquine and hydroxychloroquine as a treatment for COVID‐19

MDS Chowdhury, J Rathod… - Academic Emergency …, 2020 - Wiley Online Library
Objectives The emergence of SARS‐CoV‐2 has presented clinicians with a difficult
therapeutic dilemma. With supportive care as the current mainstay of treatment, the fatality …

Should chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review

K Gbinigie, K Frie - BJGP open, 2020 - bjgpopen.org
Background On the 11 March 2020, the World Health Organization (WHO) declared that
COVID-19 was a pandemic. To date, there are no medical treatments for COVID-19 with …

Treating COVID-19 with hydroxychloroquine (TEACH): a multicenter, double-blind randomized controlled trial in hospitalized patients

RJ Ulrich, AB Troxel, E Carmody… - Open forum …, 2020 - academic.oup.com
Background Effective therapies to combat coronavirus 2019 (COVID-19) are urgently
needed. Hydroxychloroquine (HCQ) has in vitro antiviral activity against severe acute …