Robust two-dimensional separation of intact proteins for bottom-up tandem mass spectrometry of the human CSF proteome
Cerebrospinal fluid (CSF) is produced in the brain by cells in the choroid plexus at a rate of
500 mL/day. It is the only body fluid in direct contact with the brain. Thus, any changes in the …
500 mL/day. It is the only body fluid in direct contact with the brain. Thus, any changes in the …
Proteomics analysis of human cerebrospinal fluid
X Yuan, DM Desiderio - Journal of Chromatography B, 2005 - Elsevier
Cerebrospinal fluid (CSF) is secreted from several different central nervous system (CNS)
structures, and any changes in the CSF composition will accurately reflect pathological …
structures, and any changes in the CSF composition will accurately reflect pathological …
In-depth characterization of the cerebrospinal fluid (CSF) proteome displayed through the CSF proteome resource (CSF-PR)
In this study, the human cerebrospinal fluid (CSF) proteome was mapped using three
different strategies prior to Orbitrap LC-MS/MS analysis: SDS-PAGE and mixed mode …
different strategies prior to Orbitrap LC-MS/MS analysis: SDS-PAGE and mixed mode …
Deep dive on the proteome of human cerebrospinal fluid: a valuable data resource for biomarker discovery and missing protein identification
Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders
but remains relatively under-studied compared with other biological fluids such as plasma …
but remains relatively under-studied compared with other biological fluids such as plasma …
A versatile workflow for cerebrospinal fluid proteomic analysis with mass spectrometry: a matter of choice between deep coverage and sample throughput
C Macron, A Núñez Galindo, O Cominetti… - Cerebrospinal Fluid (CSF …, 2019 - Springer
Human cerebrospinal fluid (CSF) is a sample of choice in the study of brain disorders. This
biological fluid circulates in the brain and the spinal cord and contains tissue-specific …
biological fluid circulates in the brain and the spinal cord and contains tissue-specific …
A combined dataset of human cerebrospinal fluid proteins identified by multi‐dimensional chromatography and tandem mass spectrometry
S Pan, D Zhu, JF Quinn, ER Peskind, TJ Montine… - …, 2007 - Wiley Online Library
Human cerebrospinal fluid (CSF) is an important source for studying protein biomarkers of
age‐related neurodegenerative diseases. Before characterizing biomarkers unique to each …
age‐related neurodegenerative diseases. Before characterizing biomarkers unique to each …
Identification of brain-enriched proteins in the cerebrospinal fluid proteome by LC-MS/MS profiling and mining of the Human Protein Atlas
I Begcevic, D Brinc, AP Drabovich, I Batruch… - Clinical proteomics, 2016 - Springer
Background Cerebrospinal fluid (CSF) is a proximal fluid which communicates closely with
brain tissue, contains numerous brain-derived proteins and thus represents a promising fluid …
brain tissue, contains numerous brain-derived proteins and thus represents a promising fluid …
In-depth exploration of cerebrospinal fluid by combining peptide ligand library treatment and label-free protein quantification
E Mouton-Barbosa, F Roux-Dalvai, D Bouyssié… - Molecular & Cellular …, 2010 - ASBMB
Cerebrospinal fluid (CSF) is the biological fluid in closest contact with the brain and thus
contains proteins of neural cell origin. Hence, CSF is a biochemical window into the brain …
contains proteins of neural cell origin. Hence, CSF is a biochemical window into the brain …
In-depth analysis of the human CSF proteome using protein prefractionation
G Maccarrone, I Birg, E Malisch, MC Rosenhagen… - Clinical Proteomics, 2004 - Springer
The identification of disease markers in human body fluids requires an extensive and
thorough analysis of its protein constituents. In the present study, we have extended our …
thorough analysis of its protein constituents. In the present study, we have extended our …
Proteomic Analysis of Human Ventricular Cerebrospinal Fluid from Neurologically Normal, Elderly Subjects Using Two-Dimensional LC− MS/MS
BR Wenner, MA Lovell, BC Lynn - Journal of Proteome Research, 2004 - ACS Publications
A two-dimensional liquid chromatography separation scheme coupled to tandem mass
spectrometry (2-D LC− MS/MS) was utilized to profile the proteome of human CSF …
spectrometry (2-D LC− MS/MS) was utilized to profile the proteome of human CSF …