Combination therapy with benazepril 40 mg and amlodipine 10 mg (B+ A) has been shown
to be more effective than benazepril 40 mg and hydrochlorothiazide (HCTZ) 25 mg (B+ H) in …

Background The optimal combination drug therapy for hypertension is not established,
although current US guidelines recommend inclusion of a diuretic. We hypothesized that …

Although multidrug therapy is required in order to achieve good blood pressure control in
many hypertensives, there are no studies directly comparing fixed-dose combinations as …

ACCOMPLISH is the first trial designed to compare the effects on major fatal and non‐fatal
cardiovascular endpoints of two forms of antihypertensive combination therapy: benazepril …

The combination of benazepril plus amlodipine was shown to be more effective than
benazepril plus hydrochlorothiazide in reducing cardiovascular events in the Avoiding …

Reducing blood pressure (BP) to target levels is a major priority in preventing clinical events
in hypertension. Typically this requires more than one drug, and recent guidelines on …

Background: Most patients with hypertension require two or more antihypertensive
medications to achieve blood pressure (BP) goals. This double-blind study compared the …

The Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With
Systolic Hypertension (ACCOMPLISH) trial is the first cardiovascular outcome trial designed …

Summary Background The Avoiding Cardiovascular Events through Combination Therapy
in Patients Living with Systolic Hypertension (ACCOMPLISH) trial showed that initial …

Objectives: The aim of this study was to determine which combination therapy in patients
with hypertension and diabetes most effectively decreases cardiovascular events …