Effects of plasmalogens on systemic lipopolysaccharide‐induced glial activation and β‐amyloid accumulation in adult mice

T Katafuchi, M Ifuku, S Mawatari… - Annals of the New …, 2012 - Wiley Online Library
Neuroinflammation essentially involves an activation of glial cells as the cause/effect of
neurodegenerative diseases such as Alzheimer's disease (AD). Plasmalogens (Pls) are …

Alterations in the levels of amyloid-β, phospholipid hydroperoxide, and plasmalogen in the blood of patients with Alzheimer's disease: possible interactions between …

S Yamashita, T Kiko, H Fujiwara… - Journal of …, 2016 - content.iospress.com
Aside from accumulation of amyloid-ß (Aß) peptide in the brain, Alzheimer's disease (AD)
has been reported as being associated with peroxidation of major phospholipids (eg …

Activity of choline alphoscerate on adult-onset cognitive dysfunctions: a systematic review and meta-analysis

GG Sagaro, E Traini, F Amenta - Journal of Alzheimer's …, 2023 - content.iospress.com
Background: Choline alphoscerate (alpha glyceryl phosphorylcholine, α-GPC) is a choline-
containing phospholipid used as a medicine or nutraceutical to improve cognitive function …

Results and insights from a phase I clinical trial of Lomecel‐B for Alzheimer's disease

M Brody, M Agronin, BJ Herskowitz… - Alzheimer's & …, 2023 - Wiley Online Library
Abstract Hypothesis We hypothesized that Lomecel‐B, an allogeneic medicinal signaling
cell (MSC) therapeutic candidate for Alzheimer's disease (AD), is safe and potentially …

A review on MS-based blood biomarkers for Alzheimer's disease

P Oeckl, M Otto - Neurology and Therapy, 2019 - Springer
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia and
there is no cure to date. Biomarkers in cerebrospinal fluid (CSF) are already included in the …

Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with …

MI Moré, U Freitas, D Rutenberg - Advances in therapy, 2014 - Springer
Introduction We report previously unpublished, early pilot studies performed with a brain-
health food supplement containing a proprietary blend of 100 mg phosphatidylserine (PS) …

Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease

A Kadir, N Andreasen, O Almkvist, A Wall… - Annals of …, 2008 - Wiley Online Library
Abstract Objective The effects of (−)‐phenserine (phenserine) and placebo/donepezil
treatment on regional cerebral metabolic rate for glucose (rCMRglc) and brain amyloid load …

CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study

J Ross, S Sharma, J Winston, M Nunez… - Current Alzheimer …, 2013 - ingentaconnect.com
As neuroinflammation is an early event in the pathogenesis of Alzheimer's disease, new
selective antiinflammatory drugs could lead to promising preventive strategies. We …

[HTML][HTML] Phospholipid oxidation and carotenoid supplementation in Alzheimer's disease patients

OS Ademowo, HKI Dias, I Milic, A Devitt… - Free Radical Biology …, 2017 - Elsevier
Alzheimer's disease (AD) is a progressive, neurodegenerative disease, characterised by
decline of memory, cognitive function and changes in behaviour. Generic markers of lipid …

Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial

P Scheltens, PJGH Kamphuis, FRJ Verhey… - Alzheimer's & …, 2010 - Elsevier
OBJECTIVE: To investigate the effect of a medical food on cognitive function in people with
mild Alzheimer's disease (AD). METHODS: A total of 225 drug-naïve AD patients …