Background: Oxidative stress and mitochondrial dysfunction play a vital role in the
pathogenesis of brain aging. Saponins from Panax japonicus (SPJ) have attracted much …

Context Panax japonicus is the dried rhizome of Panax japonicus CA Mey.(Araliaceae).
Saponins from Panax japonicus (SPJ) exhibit anti-oxidative and anti-aging effects. Objective …

Context Panax japonicus is the dried rhizome of Panax japonicus CA Mey.(Araliaceae).
Saponins from Panax japonicus (SPJ) exhibit anti-inflammatory and antioxidative effects …

Inhibiting oxidative damage in early stage of Alzheimer's disease (AD) is considered as a
strategy for AD treatment. Our previous study has shown that Panax notoginseng saponins …

Objective To investigate the neuroprotective effects of saponins from P anax japonicus (SPJ)
on D-galactose (D-gal)-induced brain ageing, and further explore the underlying …

Previous reports have confirmed that saponins (ginsenosides) derived from Panax ginseng.
CA Meyer exerted obvious memory‐enhancing and antiaging effects, and the simpler the …

Background Mitochondrial dysfunction is one of the distinctive features of neurons in
patients with Alzheimer's disease (AD). Intraneuronal autophagosomes selectively …

Neuroinflammation is recognized as an important pathogenic factor for aging and related
cognitive disorders. Mitogen-activated protein kinase and nuclear factor kappa B signaling …

Dammarane-type saponins, the main active ingredients of Panax notoginseng, have
substantial neuroprotective effects in different animal models of neurodegenerative …

Backgroud Sleep deprivation (SD) impairs learning and memory by inhibiting hippocampal
functioning at molecular and cellular levels. Abnormal autophagy and apoptosis are closely …