SARS-CoV-2 nucleocapsid and Nsp3 binding: an in silico study
Severe acute respiratory syndrome virus 2 (SARS-CoV-2) belongs to the single-stranded
positive-sense RNA family. The virus contains a large genome that encodes four structural …
positive-sense RNA family. The virus contains a large genome that encodes four structural …
The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients
M Shen, P Ding, G Luan, T Du, S Deng - Frontiers in Cellular and …, 2023 - frontiersin.org
Introduction With the emergence of SARS-CoV-2 mutant strains, especially the epidemic of
Omicron, it continues to evolve to strengthen immune evasion. Omicron BQ. 1 and XBB pose …
Omicron, it continues to evolve to strengthen immune evasion. Omicron BQ. 1 and XBB pose …
Analysis of three non-structural proteins, Nsp1, Nsp2, and Nsp10 of Sars-Cov-2 as pivotal target proteins for computational drug screening
Coronaviruses cause mild to severe respiratory infections. The highly contagious SARS-
CoV-2 new coronavirus caused a global outbreak of atypical viral pneumonia in late 2019 …
CoV-2 new coronavirus caused a global outbreak of atypical viral pneumonia in late 2019 …
Identification of the binding interactions of some novel antiviral compounds against Nsp1 protein from SARS-CoV-2 (COVID-19) through high throughput screening
N Chowdhury, A Bagchi - Journal of Biomolecular Structure and …, 2022 - Taylor & Francis
The SARS-CoV-2 pandemic has become a global threat. It has become very difficult to
control the spreading of the virus. The virus is a RNA virus and the virulence of the virus is …
control the spreading of the virus. The virus is a RNA virus and the virulence of the virus is …
Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach
In this study, the Nsp12–Nsp8 complex of SARS-CoV-2 was targeted with structure-based
and computer-aided drug design approach because of its vital role in viral replication …
and computer-aided drug design approach because of its vital role in viral replication …
Exploring the Potential Antiviral Properties of Nigella sativa L. Against SARS-CoV-2: Mechanisms and Prospects
Global health and economies have been significantly impacted by the COVID-19 epidemic,
leading to a race to find effective treatments and preventative measures. In this context …
leading to a race to find effective treatments and preventative measures. In this context …
Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins
YX Zheng, L Wang, WS Kong, H Chen… - Acta Biochimica et …, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global
health threat since December 2019, and there is still no highly effective drug to control the …
health threat since December 2019, and there is still no highly effective drug to control the …
[PDF][PDF] Potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12) of SARS-CoV-2
Z Ruan, C Liu, Y Guo, Z He, X Huang, X Jia, T Yang - 2020 - pdfs.semanticscholar.org
A novel coronavirus (SARS-CoV-2) that is initially found to trigger human severe respiratory
illness in Wuhan City of China in 2019, has killed 2,718 people in China by February 26 …
illness in Wuhan City of China in 2019, has killed 2,718 people in China by February 26 …
[HTML][HTML] Molecular docking studies to identify promising natural inhibitors targeting SARS-CoV-2 nsp10-nsp16 protein complex
Objectives: Unavailability of potential drugs/vaccines in the outbreak of the pandemic severe
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) have devastated the human …
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) have devastated the human …
[HTML][HTML] Nature's therapy for COVID-19: Targeting the vital non-structural proteins (NSP) from SARS-CoV-2 with phytochemicals from Indian medicinal plants
Background Containing COVID-19 is still a global challenge. It has affected the" normal"
world by targeting its economy and health sector. The effect is shifting of focus of research …
world by targeting its economy and health sector. The effect is shifting of focus of research …