One of the major virulence factors of SARS-CoV-2, NSP1, is a vital drug target due to its role
in host immune evasion through multiple pathways. NSP1 protein is associated with …

Repurposed drug molecules targeting NSP12 protein of SARS-CoV-2: An in-silico study Page 1
AIMS Molecular Science, 10(4): 322–342. DOI: 10.3934/molsci.2023019 Received: 17 …

Methyltransferases (MTases) enzymes, responsible for RNA capping into severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), are emerging important targets for the …

The evolution of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants around the globe has made the coronavirus disease 2019 (COVID-19) pandemic …

Covid-19, the first case of which was reported in Wuhan (China) in December 2019 was
found to be a strain of coronaviruses like SARS and MERS reported earlier. These viruses …

Coronaviruses are known to infect respiratory tract and intestine. These viruses possess
highly conserved viral macro domain A1pp having adenosine diphosphate (ADP)-ribose …

The need for novel antiviral treatments for coronavirus disease 2019 (COVID-19) continues
with the widespread infections and fatalities throughout the world. Severe acute respiratory …

Abstract Background Non-structural protein 1 (Nsp1), a virulence agent of SARS-CoV-2, has
emerged as an important target for drug discovery. Nsp1 shuts down the host gene function …

SARS‐CoV‐2 has been responsible for causing 6,218,308 deaths globally till date and has
garnered worldwide attention. The lack of effective preventive and therapeutic drugs against …

COVID-19, the current global pandemic has caused immense damage to human lives and
the global economy. It is instigated by the SARS-CoV-2 virus and there is an immediate …