The within-host viral kinetics of SARS-CoV-2

C Li, J Xu, J Liu, Y Zhou - BioRxiv, 2020 - biorxiv.org
In this work, we use a within-host viral dynamic model to describe the SARS-CoV-2 kinetics
in host. Chest radiograph score data are used to estimate the parameters of that model. Our …

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS …

KS Kim, K Ejima, S Iwanami, Y Fujita, H Ohashi… - PLoS …, 2021 - journals.plos.org
The scientific community is focused on developing antiviral therapies to mitigate the impacts
of the ongoing novel coronavirus disease 2019 (COVID-19) outbreak. This will be facilitated …

In vivo kinetics of SARS-CoV-2 infection and its relationship with a person's infectiousness

R Ke, C Zitzmann, DD Ho… - Proceedings of the …, 2021 - National Acad Sciences
The within-host viral kinetics of SARS-CoV-2 infection and how they relate to a person's
infectiousness are not well understood. This limits our ability to quantify the impact of …

Modeling the viral dynamics of SARS-CoV-2 infection

S Wang, Y Pan, Q Wang, H Miao, AN Brown… - Mathematical …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the
infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading …

Kinetics of SARS-CoV-2 infection in the human upper and lower respiratory tracts and their relationship with infectiousness

R Ke, C Zitzmann, RM Ribeiro, AS Perelson - MedRxiv, 2020 - medrxiv.org
SARS-CoV-2 is a human pathogen that causes infection in both the upper respiratory tract
(URT) and the lower respiratory tract (LRT). The viral kinetics of SARS-CoV-2 infection and …

In-host mathematical modelling of COVID-19 in humans

EA Hernandez-Vargas, JX Velasco-Hernandez - Annual reviews in control, 2020 - Elsevier
COVID-19 pandemic has underlined the impact of emergent pathogens as a major threat to
human health. The development of quantitative approaches to advance comprehension of …

Transmission dynamics and control measures of COVID-19 outbreak in China: a modelling study

XS Zhang, E Vynnycky, A Charlett, D De Angelis… - Scientific reports, 2021 - nature.com
COVID-19 is reported to have been brought under control in China. To understand the
COVID-19 outbreak in China and provide potential lessons for other parts of the world, in …

Transmission dynamics of the COVID‐19 outbreak and effectiveness of government interventions: A data‐driven analysis

Y Fang, Y Nie, M Penny - Journal of medical virology, 2020 - Wiley Online Library
Using the parameterized susceptible‐exposed‐infectious‐recovered model, we simulated
the spread dynamics of coronavirus disease 2019 (COVID‐19) outbreak and impact of …

Predicting the number of reported and unreported cases for the COVID-19 epidemics in China, South Korea, Italy, France, Germany and United Kingdom

Z Liu, P Magal, G Webb - Journal of theoretical biology, 2021 - Elsevier
We model the COVID-19 coronavirus epidemics in China, South Korea, Italy, France,
Germany and the United Kingdom. We identify the early phase of the epidemics, when the …

Data-based analysis, modelling and forecasting of the COVID-19 outbreak

C Anastassopoulou, L Russo, A Tsakris, C Siettos - PloS one, 2020 - journals.plos.org
Since the first suspected case of coronavirus disease-2019 (COVID-19) on December 1st,
2019, in Wuhan, Hubei Province, China, a total of 40,235 confirmed cases and 909 deaths …