[HTML][HTML] Alcohol-induced cell death in the embryo

SM Smith - Alcohol health and research world, 1997 - ncbi.nlm.nih.gov
Exposure to alcohol during gestation can have profound consequences, but not all cells
within the embryo are affected equally. Recent advances in molecular embryology have …

Increased cell death and reduced neural crest cell numbers in ethanol‐exposed embryos: partial basis for the fetal alcohol syndrome phenotype

MM Cartwright, SM Smith - Alcoholism: Clinical and …, 1995 - Wiley Online Library
Fetal alcohol syndrome (FAS) is characterized by growth retardation, craniofacial
malformations, and heart and neural defects; the cellular and molecular mechanism (s) …

[HTML][HTML] Mechanisms of alcohol-induced damage to the developing nervous system

CR Goodlett, KH Horn - Alcohol Research & Health, 2001 - ncbi.nlm.nih.gov
Numerous mechanisms likely contribute to the damaging effects of prenatal alcohol
exposure on the developing fetus and particularly the developing central nervous system …

Selective vulnerability of embryonic cell populations to ethanol‐induced apoptosis: implications for alcohol‐related birth defects and neurodevelopmental disorder

WC Dunty Jr, S Chen, RM Zucker… - Alcoholism: Clinical …, 2001 - Wiley Online Library
Background: Ethanol‐induced cell death has been characterized in very few stages of
embryogenesis. This investigation comprehensively maps patterns of both programmed and …

Exposure of embryonic cells to alcohol: contrasting effects during preimplantation and postimplantation development

DR Armant, DE Saunders - Seminars in perinatology, 1996 - Elsevier
Alcohol is a known teratogen that causes a broad variety of developmental anomalies,
including fetal growth retardation, craniofacial anomalies, and neurological disorders. The …

[引用][C] Fetal alcohol exposure: cellular toxicity and molecular events involved in toxicity

EK Michaelis - Alcoholism: Clinical and Experimental Research, 1990 - Wiley Online Library
RENATAL ETHANOL exposure leads to develop-P mental delays characterized by
decreased growth and differentiation and by visceral and craniofacial malformation. I4 Not …

Ethanol‐induced neural crest apoptosis is coincident with their endogenous death, but is mechanistically distinct

MM Cartwright, LL Tessmer… - Alcoholism: Clinical and …, 1998 - Wiley Online Library
The ability of both acute and chronic ethanol exposures to elicit cell death within specific
embryonic and adult tissues is believed to partly underlie ethanol's pathogenicity; however …

Drug-induced apoptosis: mechanism by which alcohol and many other drugs can disrupt brain development

CE Creeley, JW Olney - Brain sciences, 2013 - mdpi.com
Maternal ingestion of alcohol during pregnancy can cause a disability syndrome termed
Fetal Alcohol Spectrum Disorder (FASD), which may include craniofacial malformations …

[HTML][HTML] Fetal alcohol exposure: the common toll

MR Nakhoul, KE Seif, N Haddad… - Journal of alcoholism …, 2017 - ncbi.nlm.nih.gov
Alcohol has always been present in human life, and currently it is estimated that 50% of
women of childbearing age consume alcohol. It has become increasingly clear over the last …

The effects of alcohol on fetal development

KL Jones - Birth Defects Research Part C: Embryo Today …, 2011 - Wiley Online Library
Prenatal exposure to alcohol has profound effects on many aspects of fetal development.
Although alterations of somatic growth and specific minor malformations of facial structure …