Recent advances highlight the involvement of histone acetyltransferases in transcriptional
activation and histone deacetylases in transcriptional repression. Transcription factors …

Histone acetylation regulates many cellular processes, and specific acetylation marks, either
singly or in combination, produce distinct outcomes. For example, the acetylation pattern on …

Histone acetylation and deacetylation in the yeast Saccharomyces cerevisiae occur by
targeting acetyltransferase and deacetylase enzymes to gene promoters and, in an …

A key event in the regulation of eukaryotic gene expression is the posttranslational
modification of nucleosomal histones, which converts regions of chromosomes into …

Histone acetyltransferases and histone deacetylases regulate the acetylation of histones
and transcription factors, and in doing so have major roles in the control of cell fate. Many …

What's Up and Down with Histone Deacetylation and Transcription?: Cell Skip to Main Content
Advertisement Cell This journal offers authors two options (open access or subscription) to …

The fact that histones are modified by acetylation has been known for almost 30 years. The
recent identification of enzymes that regulate histone acetylation has revealed a broader use …

Reversible acetylation of lysines on the amino-terminal tails of nucleosomal histones is
correlated with changes in chromatin structure and transcription. The recent characterization …

The organization of eukaryotic chromatin has a major impact on all nuclear processes
involving DNA substrates. Gene expression is affected by the positioning of individual …

Post-synthetic modification of histone proteins in chromatin architecture plays a central role
in the epigenetic regulation of transcription. Histone acetylation and methylation are the two …