COVID‐19 is characterized by dysregulated immune responses, metabolic dysfunction and
adverse effects on the function of multiple organs. To understand host responses to COVID …

Viral sepsis has been proposed as an accurate term to describe all multisystemic
dysregulations and clinical findings in severe and critically ill COVID-19 patients. The …

Summary The coronavirus disease 2019 (COVID-19) pandemic is a global public health
crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here …

Abstract Coronavirus disease 2019 (COVID-19) has gained prominence as a global
pandemic. Studies have suggested that systemic alterations persist in a considerable …

The mortality risk of coronavirus disease 2019 (COVID-19) patients has been linked to the
cytokine storm caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

The reason why most individuals with COVID-19 have relatively limited symptoms while
other develop respiratory distress with life-threatening complications remains unknown …

The COVID-19 pandemic caused by SARS-CoV-2 challenges the understanding of factors
affecting disease progression and severity. The identification of prognostic biomarkers and …

Early detection and effective treatment of severe COVID-19 patients remain major
challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID …

A deeper understanding of COVID‐19 on human molecular pathophysiology is urgently
needed as a foundation for the discovery of new biomarkers and therapeutic targets. Here …

Severely-afflicted COVID-19 patients can exhibit disease manifestations representative of
sepsis, including acute respiratory distress syndrome and multiple organ failure. We …