[HTML][HTML] Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

MP Nägele, B Haubner, FC Tanner, F Ruschitzka… - Atherosclerosis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary
complications such as acute myocardial injury, renal failure or thromboembolic events. A …

[HTML][HTML] Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications

Z Ma, KY Yang, Y Huang, KO Lui - Journal of Molecular and Cellular …, 2022 - Elsevier
The global propagation of SARS-CoV-2 leads to an unprecedented public health
emergency. Despite that the lungs are the primary organ targeted by COVID-19, systemic …

[HTML][HTML] Evaluation of endothelial dysfunction and inflammatory vasculopathy after SARS-CoV-2 infection—a cross-sectional study

P Jud, P Gressenberger, V Muster, A Avian… - Frontiers in …, 2021 - frontiersin.org
Background: Rising data suggest that COVID-19 affects vascular endothelium while the
underlying mechanisms promoting COVID-19-associated endothelial dysfunction and …

[HTML][HTML] Pathophysiological association of endothelial dysfunction with fatal outcome in COVID-19

T Maruhashi, Y Higashi - International Journal of Molecular Sciences, 2021 - mdpi.com
The outbreak of coronavirus disease 2019 (COVID-19) caused by the betacoronavirus
SARS-CoV-2 is now a worldwide challenge for healthcare systems. Although the leading …

[HTML][HTML] Endothelial dysfunction in COVID-19: lessons learned from coronaviruses

E Gavriilaki, P Anyfanti, M Gavriilaki, A Lazaridis… - Current hypertension …, 2020 - Springer
Abstract Purpose of Review To review current literature on endothelial dysfunction with
previous coronaviruses, and present available data on the role of endothelial dysfunction in …

[HTML][HTML] Is the endothelium the missing link in the pathophysiology and treatment of COVID-19 complications?

P Castro, M Palomo, AB Moreno-Castaño… - … drugs and therapy, 2022 - Springer
Patients with COVID-19 present a wide spectrum of disease severity, from asymptomatic
cases in the majority to serious disease leading to critical care and even death. Clinically …

Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic …

PC Evans, GE Rainger, JC Mason… - Cardiovascular …, 2020 - academic.oup.com
The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and
illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also …

[HTML][HTML] Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …

[HTML][HTML] Endothelial dysfunction in COVID-19: a unifying mechanism and a potential therapeutic target

P Ambrosino, IL Calcaterra, M Mosella, R Formisano… - Biomedicines, 2022 - mdpi.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generated a
worldwide emergency, until the declaration of the pandemic in March 2020. SARS-CoV-2 …

[HTML][HTML] The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection

S Pons, S Fodil, E Azoulay, L Zafrani - Critical care, 2020 - Springer
In severe SARS-CoV-2 infections, emerging data including recent histopathological studies
have emphasized the crucial role of endothelial cells (ECs) in vascular dysfunction …