[HTML][HTML] Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
Neutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-2
spike protein are among the most promising approaches against COVID-19,. A bispecific …
spike protein are among the most promising approaches against COVID-19,. A bispecific …
[HTML][HTML] Potently neutralizing and protective human antibodies against SARS-CoV-2
The ongoing pandemic of coronavirus disease 2019 (COVID-19), which is caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a major threat to global health …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a major threat to global health …
[HTML][HTML] Human neutralizing antibodies elicited by SARS-CoV-2 infection
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a global health emergency that …
respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a global health emergency that …
[HTML][HTML] SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Abstract The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
[HTML][HTML] A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2
R Shi, C Shan, X Duan, Z Chen, P Liu, J Song, T Song… - Nature, 2020 - nature.com
An outbreak of coronavirus disease 2019 (COVID-19),–, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …
[PDF][PDF] Stabilized coronavirus spike stem elicits a broadly protective antibody
Current coronavirus (CoV) vaccines primarily target immunodominant epitopes in the S1
subunit, which are poorly conserved and susceptible to escape mutations, thus threatening …
subunit, which are poorly conserved and susceptible to escape mutations, thus threatening …
[HTML][HTML] Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continues,
with devasting consequences for human lives and the global economy,. The discovery and …
with devasting consequences for human lives and the global economy,. The discovery and …
[HTML][HTML] Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …
[HTML][HTML] An engineered bispecific human monoclonal antibody against SARS-CoV-2
Z Li, S Li, G Zhang, W Peng, Z Chang, X Zhang… - Nature …, 2022 - nature.com
The global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
requires effective therapies against coronavirus disease 2019 (COVID-19), and neutralizing …
requires effective therapies against coronavirus disease 2019 (COVID-19), and neutralizing …
[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
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