Asynthesis, crystal structures and in vitro anticancer studies of new thiosemicarbazone derivatives

MA Hussein, MA Iqbal, M Asif, RA Haque… - … , Sulfur, and Silicon …, 2015 - Taylor & Francis
Thiosemicarbazones are an important class of compounds having significant biological
properties. These compounds are used as stable ligands for the synthesis of coordination …

[HTML][HTML] Synthesis, structural elucidation and cytotoxicity of new thiosemicarbazone derivatives

MA Hussein, MA Iqbal, MI Umar, RA Haque… - Arabian Journal of …, 2019 - Elsevier
Abstract Syntheses and characterization (1 H & 13 C NMR and CHN) of four new
thiosemicarbazone derivatives (1–4) are reported. The molecular structures of compounds 1 …

Novel thiosemicarbazone derivatives as potential antitumor agents: Synthesis, physicochemical and structural properties, DNA interactions and antiproliferative …

I Đilović, M Rubčić, V Vrdoljak, SK Pavelić… - Bioorganic & medicinal …, 2008 - Elsevier
The paper describes synthesis of several novel thiosemicarbazone derivatives. Furthermore,
crystal and molecular structure of 4-diethylamino-salicylaldehyde 4 …

Cytotoxicity and structure–activity relationships of four α-N-heterocyclic thiosemicarbazone derivatives crystal structure of 2-acetylpyrazine thiosemicarbazone

MX Li, CL Chen, CS Ling, J Zhou, BS Ji, YJ Wu… - Bioorganic & medicinal …, 2009 - Elsevier
A series of thiosemicarbazone ligands, HL1 (2-acetylpyrazine thiosemicarbazone), HL2 (2-
acetylpyrazine N (4)-methylthiosemicarbazone), HL3 (2-benzoylpyridine …

Crystal Structure and Conformation Study of 4-Chlorobenzaldehyde Thiosemicarbazone Derivative

N Sampath, R Mathews, MN Ponnuswamy - Journal of Chemical …, 2010 - Springer
Thiosemicarbazones (TSCs) are very versatile tridentate ligands having the ability to bind
transition metal ions by bonding through sulfur and hydrazinic terminal nitrogen atoms. TSC …

Thiazole-based thiosemicarbazones: Synthesis, cytotoxicity evaluation and molecular docking study

SM Gomha, HA Abdelhady, DZH Hassain… - Drug design …, 2021 - Taylor & Francis
Introduction Hybrid drug design has developed as a prime method for the development of
novel anticancer therapies that can theoretically solve much of the pharmacokinetic …

Synthesis, Characterization and Hirshfeld Surface Analysis of Some Thiosemicarbazones Containing a Five-Membered Ring

II Ozturk - Journal of Structural Chemistry, 2023 - Springer
Thiosemicarbazones, which are multidentate ligands, are considered as one of the most
important classes of organic compounds due to their broad spectrum of pharmacological …

Novel thiosemicarbazone derivatives and their metal complexes: Recent development

NP Prajapati, HD Patel - Synthetic Communications, 2019 - Taylor & Francis
Thiosemicarbazones (TSCs) have turned out as an important class of N, S-donor ligands
over a span of time due to their variable donor properties, structural diversity and biological …

Synthesis, Spectroscopic Characterization, Structural Studies, and In Vitro Antitumor Activities of Pyridine‐3‐carbaldehyde Thiosemicarbazone Derivatives

W Hernández, F Carrasco, A Vaisberg… - Journal of …, 2020 - Wiley Online Library
Eight new thiosemicarbazone derivatives, 6‐(1‐trifluoroethoxy) pyridine‐3‐carbaldehyde
thiosemicarbazone (1), 6‐(4′‐fluorophenyl) pyridine‐3‐carbaldehyde thiosemicarbazone …

Synthesis, characterization and antitumor activities of some novel thiazinones and thiosemicarbazones derivatives

SAA Anand, K George, NS Thomas… - Phosphorus, Sulfur, and …, 2020 - Taylor & Francis
Two series of thiazinone and thiosemicarbazone derivatives (1-12) were synthesized using
2, 4-diaryl-3-azabicyclo [3.3. 1] nonan-9-ones (ABNs) and 3–alkyl–2, 6–diarylpiperidin–4 …