B-precursor acute lymphoblastic leukemia (B-ALL) is the most common childhood tumor and
the leading cause of cancer-related death in children and young adults. The majority of B …

To resolve the genetic heterogeneity within pediatric high-risk B-precursor acute
lymphoblastic leukemia (ALL), a clinically defined poor-risk group with few known recurring …

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and a
leading case of childhood cancer death. The last decade has witnessed a transformation in …

Genomic analyses have revolutionized our understanding of the biology of B-progenitor
acute lymphoblastic leukemia (ALL). Studies of thousands of cases across the age spectrum …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …

B-lymphoblastic leukemia/lymphoma, also known as B-acute lymphoblastic leukemia, is
derived from B-cell progenitors. B-acute lymphoblastic leukemia occurs predominantly in …

A key goal in cancer research is to identify the total complement of genetic and epigenetic
alterations that contribute to tumorogenesis. We are currently witnessing the rapid evolution …

Acute lymphoblastic leukaemia (ALL) occurs in approximately 1: 1500 children and is less
frequently found in adults. The most common immunophenotype of ALL is the B cell lineage …

Acute lymphoblastic leukemia (ALL) is mainly a disease of childhood that arises from
recurrent genetic insults that block precursor B and T cell differentiation and drive aberrant …

Most B cell precursor acute lymphoblastic leukemia (BCP ALL) can be classified into known
major genetic subtypes, while a substantial proportion of BCP ALL remains poorly …