[HTML][HTML] Armed oncolytic viruses: A kick-start for anti-tumor immunity

JF De Graaf, L de Vor, RAM Fouchier… - Cytokine & growth factor …, 2018 - Elsevier
Oncolytic viruses (OVs), viruses that specifically result in killing tumor cells, represent a
promising class of cancer therapy. Recently, the focus in the OV therapy field has shifted …

[HTML][HTML] Oncolytic ImmunoViroTherapy: A long history of crosstalk between viruses and immune system for cancer treatment

S Feola, S Russo, E Ylösmäki, V Cerullo - Pharmacology & therapeutics, 2022 - Elsevier
Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific
anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic …

Oncolytic viruses: newest frontier for cancer immunotherapy

MM Rahman, G McFadden - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic viruses (OVs) are viruses that selectively target and kill cancer
cells while sparing normal ones. OVs are from diverse families of viruses, but naturally …

Arming oncolytic viruses to leverage antitumor immunity

TD de Gruijl, AB Janssen… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Over the past decade, the cytolytic capabilities of oncolytic viruses (OVs),
exploited to selectively eliminate neoplastic cells, have become secondary to their use to …

Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements

CO Yun, JW Hong, AR Yoon - Frontiers in Immunology, 2022 - frontiersin.org
Oncolytic viruses (OVs) have been gaining attention in the pharmaceutical industry as a
novel immunotherapeutic and therapeutic adjuvant due to their ability to induce and boost …

Engineering strategies to enhance oncolytic viruses in cancer immunotherapy

Y Tian, D Xie, L Yang - Signal transduction and targeted therapy, 2022 - nature.com
Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for
patients with tumors. They preferentially target and kill tumor cells, leaving healthy cells …

Oncolytic viruses and the immune system: the dynamic duo

AL De Matos, LS Franco, G McFadden - Molecular Therapy-Methods & …, 2020 - cell.com
Oncolytic viruses (OVs) constitute a new and promising immunotherapeutic approach
toward cancer treatment. This therapy takes advantage of the natural propensity of most …

Combination immunotherapy using oncolytic virus for the treatment of advanced solid tumors

CM Oh, HJ Chon, C Kim - International journal of molecular sciences, 2020 - mdpi.com
Oncolytic virus (OV) is a new therapeutic strategy for cancer treatment. OVs can selectively
infect and destroy cancer cells, and therefore act as an in situ cancer vaccine by releasing …

Oncolytic viruses and their application to cancer immunotherapy

EA Chiocca, SD Rabkin - Cancer immunology research, 2014 - AACR
Oncolytic viruses (OV) selectively replicate and kill cancer cells and spread within the tumor,
while not harming normal tissue. In addition to this direct oncolytic activity, OVs are also very …

Oncolytic viruses—immunotherapeutics on the rise

BA Keller, JC Bell - Journal of Molecular Medicine, 2016 - Springer
The oncolytic virus (OV) field has entered an exciting period in its evolution in which our
basic understanding of viral biology and anti-cancer potential are being actively translated …