A bacteriophage-based, highly efficacious, needle-and adjuvant-free, mucosal COVID-19 vaccine
ABSTRACT The US Food and Drug Administration-authorized mRNA-and adenovirus-
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
Bacteriophage T4 as a Protein-Based, Adjuvant-and Needle-Free, Mucosal Pandemic Vaccine Design Platform
The COVID-19 pandemic has transformed vaccinology. Rapid deployment of mRNA
vaccines has saved countless lives. However, these platforms have inherent limitations …
vaccines has saved countless lives. However, these platforms have inherent limitations …
SARS-CoV-2: immunity, challenges with current vaccines, and a novel perspective on mucosal vaccines
The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …
spread, disease severity, hospitalizations, and deaths. However, the first-generation …
[HTML][HTML] Mucosal COVID-19 vaccines: Risks, benefits and control of the pandemic
D Miteva, M Peshevska-Sekulovska… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Based on mucosal immunization to promote both mucosal and systemic immune responses,
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …
Adenoviral-vectored next-generation respiratory mucosal vaccines against COVID-19
The world is in need of next-generation COVID-19 vaccines. Although first-generation
injectable COVID-19 vaccines continue to be critical tools in controlling the current global …
injectable COVID-19 vaccines continue to be critical tools in controlling the current global …
[HTML][HTML] Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines
V Mouro, A Fischer - Mucosal immunology, 2022 - Elsevier
The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
[HTML][HTML] Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques
Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have
focused on systemic immunization, here we compared the protective efficacy of 2 …
focused on systemic immunization, here we compared the protective efficacy of 2 …
Intranasal administration of a single dose of MVA-based vaccine candidates against COVID-19 induced local and systemic immune responses and protects mice from …
P Pérez, D Astorgano, G Albericio, S Flores… - Frontiers in …, 2022 - frontiersin.org
Current coronavirus disease-19 (COVID-19) vaccines are administered by the intramuscular
route, but this vaccine administration failed to prevent severe acute respiratory syndrome …
route, but this vaccine administration failed to prevent severe acute respiratory syndrome …
Intranasal single-replication influenza vector induces cross-reactive serum and mucosal antibodies against SARS-CoV-2 variants
MJ Moser, L Hill-Batorski, RA Bowen, SM Matejka… - Vaccines, 2023 - mdpi.com
Current SARS-CoV-2 vaccines provide protection for COVID-19-associated hospitalization
and death, but remain inefficient at inhibiting initial infection and transmission. Despite …
and death, but remain inefficient at inhibiting initial infection and transmission. Despite …