Involvement of circRNAs in the Development of Heart Failure

G Sygitowicz, D Sitkiewicz - International Journal of Molecular Sciences, 2022 - mdpi.com
In recent years, interest in non-coding RNAs as important physiological regulators has
grown significantly. Their participation in the pathophysiology of cardiovascular diseases is …

[HTML][HTML] Advance in circular RNA modulation effects of heart failure

L Jiang, X Wang, X Zhan, S Kang, H Liu, Y Luo, L Lin - Gene, 2020 - Elsevier
CircRNA (circular RNA) is a kind of closed circular structure of noncoding RNA molecules
without 5′ hat structure and 3′ polyA, mainly located in the cytoplasm or stored in …

[HTML][HTML] CircRNAs open a new era in the study of cardiovascular disease

Z Yu, Q Huang, Q Zhang, H Wu… - … Journal of Molecular …, 2021 - spandidos-publications.com
Circular RNAs (circRNAs) are non‑coding RNAs that are found in the cytoplasm or stored in
the exosomes, where they are not affected by RNA exonucleases. CircRNAs are widely …

Circle the cardiac remodeling with circRNAs

T Yang, T Long, T Du, Y Chen, Y Dong… - Frontiers in …, 2021 - frontiersin.org
Cardiac remodeling occurs after the heart is exposed to stress, which is manifested by
pathological processes such as cardiomyocyte hypertrophy and apoptosis, dendritic cells …

[HTML][HTML] Role of circular RNA in myocardial ischemia and ageing-related diseases

X Gao, X Tian, Y Huang, R Fang, G Wang, D Li… - Cytokine & Growth …, 2022 - Elsevier
Circular RNA (circRNA) is a new endogenous transcription product, which has attracted
significant attention in RNA biology research. CircRNA comprise exons or introns involved in …

The function and therapeutic potential of circular RNA in cardiovascular diseases

K Wang, XQ Gao, T Wang, LY Zhou - Cardiovascular Drugs and Therapy, 2021 - Springer
Circular RNA (circRNA) has a closed-loop structure, and its 3'and 5'ends are directly
covalently connected by reverse splicing, which is more stable than linear RNA. CircRNAs …

Circular RNA in cardiovascular disease: Expression, mechanisms and clinical prospects

Y Tang, J Bao, J Hu, L Liu, DY Xu - Journal of cellular and …, 2021 - Wiley Online Library
Circular RNAs (circRNAs) are a group of covalently closed, endogenous, non‐coding RNAs,
which exist widely in human tissues including the heart. Increasing evidence has shown that …

Circular RNAs in cardiovascular disease: an overview

X Fan, X Weng, Y Zhao, W Chen… - BioMed research …, 2017 - Wiley Online Library
Circular RNA (circRNA), a novel type of endogenous noncoding RNA (ncRNA), has become
a research hotspot in recent years. CircRNAs are abundant and stably exist in creatures …

The emerging landscape of circular RNA in cardiovascular diseases

M Zhou, JM Yang, X Xiong - Journal of Molecular and Cellular Cardiology, 2018 - Elsevier
Circular RNAs (circRNAs), a large novel type of endogenous transcripts, have become a
new research hotspot in the field of RNA biology. CircRNAs are mainly generated from …

Circular RNA: a new expectation for cardiovascular diseases

Q Xie, Y Ma, Z Ren, T Gu, Z Jiang - Journal of Cellular …, 2024 - Wiley Online Library
Circular RNA (circRNA) is a class of RNA with the 5'and 3'ends connected covalently to form
a closed loop structure and characterized by high stability, conserved sequences and tissue …