Evidence for accelerated decline of functional brain network efficiency in schizophrenia

JM Sheffield, G Repovs, MP Harms… - Schizophrenia …, 2016 - academic.oup.com
Previous work suggests that individuals with schizophrenia display accelerated aging of
white matter integrity, however, it is still unknown whether functional brain networks also …

Functional connectivity and brain networks in schizophrenia

ME Lynall, DS Bassett, R Kerwin… - Journal of …, 2010 - Soc Neuroscience
Schizophrenia has often been conceived as a disorder of connectivity between components
of large-scale brain networks. We tested this hypothesis by measuring aspects of both …

Graph metrics of structural brain networks in individuals with schizophrenia and healthy controls: group differences, relationships with intelligence, and genetics

RA Yeo, SG Ryman, MP Van Den Heuvel… - Journal of the …, 2016 - cambridge.org
Objectives: One of the most prominent features of schizophrenia is relatively lower general
cognitive ability (GCA). An emerging approach to understanding the roots of variation in …

On the integrity of functional brain networks in schizophrenia, Parkinson's disease, and advanced age: Evidence from connectivity‐based single‐subject classification

RN Pläschke, EC Cieslik, VI Müller… - Human brain …, 2017 - Wiley Online Library
Previous whole‐brain functional connectivity studies achieved successful classifications of
patients and healthy controls but only offered limited specificity as to affected brain systems …

Schizophrenia symptoms and brain network efficiency: A resting-state fMRI study

TW Su, TW Hsu, YC Lin, CP Lin - Psychiatry Research: Neuroimaging, 2015 - Elsevier
Schizophrenia is a condition marked by a disrupted brain functional network. In
schizophrenia, the brain network is characterized by reduced distributed information …

Altered brain network dynamics in schizophrenia: a cognitive electroencephalography study

J Naim-Feil, M Rubinson, D Freche… - Biological Psychiatry …, 2018 - Elsevier
Background Alterations in the dynamic coordination of widespread brain networks are
proposed to underlie cognitive symptoms of schizophrenia. However, there is limited …

Upper cortical layer–driven network impairment in schizophrenia

MY Batiuk, T Tyler, K Dragicevic, S Mei, R Rydbirk… - Science …, 2022 - science.org
Schizophrenia is one of the most widespread and complex mental disorders. To
characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing …

Transdiagnostic associations between functional brain network integrity and cognition

JM Sheffield, S Kandala, CA Tamminga… - JAMA …, 2017 - jamanetwork.com
Importance Cognitive impairment occurs across the psychosis spectrum and is associated
with functional outcome. However, it is unknown whether these shared manifestations of …

Cognitive effort and schizophrenia modulate large-scale functional brain connectivity

CL Brandt, T Kaufmann, I Agartz, K Hugdahl… - Schizophrenia …, 2015 - academic.oup.com
Schizophrenia (SZ) is characterized by cognitive dysfunction and disorganized thought, in
addition to hallucinations and delusions, and is regarded a disorder of brain connectivity …

Compromised small-world efficiency of structural brain networks in schizophrenic patients and their unaffected parents

H Yan, L Tian, Q Wang, Q Zhao, W Yue, J Yan… - Neuroscience …, 2015 - Springer
Several lines of evidence suggest that efficient information integration between brain
regions is disrupted in schizophrenia. Abnormalities in white matter tracts that interconnect …