Animal models of COVID-19 II. Comparative immunology

RT Veenhuis, CJ Zeiss - ILAR journal, 2021 - academic.oup.com
Developing strong animal models is essential for furthering our understanding of how the
immune system functions in response to Severe Acute Respiratory Syndrome Coronavirus 2 …

[HTML][HTML] Experimental animal models of coronavirus infections: strengths and limitations

MAB Casel, RG Rollon, YK Choi - Immune Network, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since the emergence of SARS-CoV-2 in the human …

SARS-CoV-2 immunity in animal models

Z Chen, Y Yuan, Q Hu, A Zhu, F Chen, S Li… - Cellular & molecular …, 2024 - nature.com
The COVID-19 pandemic, which was caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a worldwide health crisis due to its …

A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies

AO Hassan, JB Case, ES Winkler, LB Thackray… - Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic
with millions of human infections. One limitation to the evaluation of potential therapies and …

Mouse models in COVID-19 research: analyzing the adaptive immune response

S Clever, A Volz - Medical microbiology and immunology, 2023 - Springer
The emergence of SARS-CoV-2, the severe acute respiratory syndrome coronavirus type 2
causing the COVID-19 pandemic, resulted in a major necessity for scientific …

Animal models for SARS‐CoV‐2 infection and pathology

Z Bi, W Hong, J Yang, S Lu, X Peng - MedComm, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the etiology of
coronavirus disease 2019 (COVID‐19) pandemic. Current variants including Alpha, Beta …

Cell and animal models of SARS-CoV-2 pathogenesis and immunity

SR Leist, A Schäfer… - Disease models & …, 2020 - journals.biologists.com
The spread of the novel virus SARS coronavirus 2 (SARS-CoV-2) was explosive, with cases
first identified in December 2019, and> 22 million people infected and> 775,000 deaths as …

Thinking Outside the Box: Utilizing Nontraditional Animal Models for COVID-19 Research

S Gunasekara, M Tamil Selvan, CA Miller… - International Journal of …, 2022 - mdpi.com
The ongoing COVID-19 pandemic continues to affect the lives, wellbeing, and stability of
communities worldwide. The race to save human lives is critical, and the development of …

Natural and genetically-modified animal models to investigate pulmonary and extrapulmonary manifestations of COVID-19

S Tiwari, G Goel, A Kumar - International Reviews of Immunology, 2024 - Taylor & Francis
Abstract Coronavirus disease-19 (COVID-19), a pandemic caused by Severe Acute
Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), is a primarily respiratory tract disease …

Understanding COVID-19: from dysregulated immunity to vaccination status quo

RA Escobedo, DK Singh, D Kaushal - Frontiers in Immunology, 2021 - frontiersin.org
The development of vaccines against infectious diseases has helped us battle the greatest
threat to public health. With the emergence of novel viruses, targeted immunotherapeutics …