Background Complex psychiatric traits have long been thought to be the result of a
combination of genetic and environmental factors, and gene–environment interactions are …

Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …

A decade of research has demonstrated the explanatory potential of interplay between
genetic variants and environmental factors in the development of common mental disorders …

This article serves to outline a research paradigm to investigate main effects and interactions
of genes, environment, and development on behavior and psychiatric illness. We provide a …

Background Psychiatric disorders run in families, and early twin, family and adoption studies
confirmed that this was due in part to shared genetic inheritance. While candidate gene …

Studying how genetic predispositions come together with environmental factors to contribute
to complex behavioral outcomes has great potential for advancing the understanding of the …

There has been an explosion of interest in studying gene-environment interactions (GxE) as
they relate to the development of psychopathology. In this article, I review different …

Family studies have demonstrated genetic influences on environmental exposure: the
phenomenon of gene–environment correlation (rGE). A few molecular genetic studies have …

Modern research acknowledges that psychopathology and individual differences in normal
development are the joint products of both biological and social influences. Although there …

Gene–environment interplay is a general term that covers several divergent concepts with
different meanings and different implications. In this review, we evaluate research evidence …