The brain is a highly energetic organ. Although the brain can consume metabolic substrates,
such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult …

Abstract Magnetic Resonance Spectroscopy (MRS) allows for a non-invasive and non-
ionizing determination of in vivo tissue concentrations and metabolic turn-over rates of more …

AIM: To discuss the advantages of ultra-high field (7T) for 1 H and 13 C magnetic resonance
spectroscopy (MRS) studies of metabolism. METHODS: Measurements of brain metabolites …

Introduction Ultra-high-field magnetic resonance (MR) systems (7 T and 9.4 T) offer the
ability to probe human brain metabolism with enhanced precision. Here, we present the …

Abstract Magnetic Resonance Spectroscopic Imaging (MRSI) of the brain enables insights
into the metabolic changes and fluxes in diseases such as tumors, multiple sclerosis …

Brain energy metabolism relies predominantly on glucose and oxygen utilization to generate
biochemical energy in the form of adenosine triphosphate (ATP). ATP is essential for …

1H and 31P nuclear magnetic resonance spectroscopy allows to detect and to measure in
vivo and non-invasively the concentrations of biologically relevant compounds associated to …

MR spectroscopy (MRS) is capable of probing information on metabolites within the body
but suffers from an inherently low sensitivity. In the case of proton (1 H) MRS, significant …

In vivo 31P MRS provides a unique tool for studying bioenergetics of living organs. Although
its utility has been limited by the relatively low 31P NMR sensitivity, increasing magnetic field …

In vivo MRS is a non‐invasive measurement technique used not only in humans, but also in
animal models using high‐field magnets. MRS enables the measurement of metabolite …