We have performed a systematic temporal and spatial expression profiling of the developing
mouse kidney using Compugen long-oligonucleotide microarrays. The activity of 18,000 …

We set out to define patterns of gene expression during kidney organogenesis by using high-
density DNA array technology. Expression analysis of 8,740 rat genes revealed five discrete …

The functional unit of the kidney is the nephron. During its organogenesis, the mammalian
metanephric kidney generates thousands of nephrons over a protracted period of fetal life …

Kidney development is based on differential cell-type-specific expression of a vast number
of genes. While multiple critical genes and pathways have been elucidated, a genome-wide …

A catalogue of gene expression in the developing kidney. Background Although many
genes with important function in kidney morphogenesis have been described, it is clear that …

The E11. 5 mouse metanephros is comprised of a T-stage ureteric epithelial tubule sub-
divided into tip and trunk cells surrounded by metanephric mesenchyme (MM). Tip cells are …

Human kidney function is underpinned by approximately 1,000,000 nephrons, although the
number varies substantially, and low nephron number is linked to disease. Human kidney …

In Mammals, kidney development proceeds in three stages (reviewed in 1). The first two
stages lead to the formation of transient structures, the pronephros and the mesonephros …

Recent advances in the generation of kidney organoids and the culture of primary nephron
progenitors from mouse and human have been based on knowledge of the molecular basis …

Changes in gene expression patterns in the ureteric bud and metanephric mesenchyme in
models of kidney development. Background In a recent study, the pattern of gene …