Despite tremendous progress in the understanding of COVID-19, mechanistic insight into
immunological, disease-driving factors remains limited. We generated maVie16, a mouse …

The successive emergences and accelerating spread of novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) lineages and evolved resistance to some ongoing …

Due to differences in human and murine angiotensin converting enzyme 2 (ACE-2) receptor,
initially available SARS-CoV-2 isolates could not infect mice. Here we show that serial …

The COVID-19 pandemic has covered more than 200 countries and regions around the
world since its outbreak in January 2020. To date, the SARS-CoV-2 virus has caused> 1.2 …

COVID-19 is the most consequential pandemic of the 21st century. Since the earliest stage
of the 2019-2020 epidemic, animal models have been useful in understanding the …

This article reviews the correlation between angiotensin‐converting enzyme 2 (ACE2) and
severe risk factors for coronavirus disease 2019 (COVID‐19) and the possible mechanisms …

Vaccine hesitancy and emergence of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variants of concern (VOCs) escaping vaccine-induced immune responses …

There is pressing urgency to understand the pathogenesis of the severe acute respiratory
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS …

The coronavirus disease 2019 pandemic has made deployment of an effective vaccine a
global health priority. We evaluated the protective activity of a chimpanzee adenovirus …

SARS-CoV-2 virus causes upper and lower respiratory diseases including pneumonia, and
in some cases, leads to lethal pulmonary failure. Angiotensin converting enzyme-2 (ACE2) …