JR Teijaro - Seminars in immunopathology, 2017 - Springer
The term Bcytokine storm^ has been adopted in the past several decades as a phrase to describe the aberrant production of soluble mediators and the accompanying …
DJ Stearns-Kurosawa, MF Osuchowski… - Annual review of …, 2011 - annualreviews.org
Sepsis is a serious clinical condition that represents a patient's response to a severe infection and has a very high mortality rate. Normal immune and physiologic responses …
Sepsis is currently listed as the 13th leading cause of death in the United States, and it is on the rise. Factors thought to account for this recent increase include an aging population …
D Jarczak, S Kluge, A Nierhaus - Frontiers in medicine, 2021 - frontiersin.org
Sepsis is a life-threatening condition and a global disease burden. Today, the heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …
A Marques, C Torre, R Pinto, B Sepodes… - Journal of Clinical …, 2023 - mdpi.com
Sepsis is currently defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, and it affects over 25 million people every year. Even more …
JC Marshall - Journal of Leucocyte Biology, 2008 - academic.oup.com
The clinical syndrome of sepsis encompasses a highly heterogeneous group of clinical disorders, varying with respect to the site, bacteriology, and even presence of infection and …
L Ulloa, KJ Tracey - Trends in molecular medicine, 2005 - cell.com
Sepsis–the most common cause of death in hospitalized patients–affects over 18 million people worldwide and has an expected 1% increase of incidence per year. Recent clinical …
W Schulte, J Bernhagen, R Bucala - Mediators of inflammation, 2013 - Wiley Online Library
Sepsis and septic shock are among the leading causes of death in intensive care units worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …
KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
Immune cells secrete small protein molecules that aim for cell–cell communications. These small molecules are called cytokines. Targeting cancer cells with administration of bispecific …