Long Noncoding RNA UCA1 in Gastrointestinal Cancers: Molecular Regulatory Roles and Patterns, Mechanisms, and Interactions

S Ramli, MS Sim, RM Guad, SCB Gopinath… - Journal of …, 2021 - Wiley Online Library
The rising trend of gastrointestinal (GI) cancer has become a global burden due to its
aggressive nature and poor prognosis. Long noncoding RNAs (lncRNAs) have recently …

[HTML][HTML] Overexpression of long non-coding RNA UCA1 predicts a poor prognosis in patients with esophageal squamous cell carcinoma

JY Li, X Ma, CB Zhang - International journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Abstract Introduction: Long non-coding RNAs (lncRNAs) have been shown to have
important regulatory roles in cancer biology, and the lncRNA UCA1 is upregulated in several …

The prognostic value and mechanisms of lncRNA UCA1 in human cancer

F Yao, Q Wang, Q Wu - Cancer management and research, 2019 - Taylor & Francis
Long noncoding RNAs (lncRNAs), longer than 200 nucleotides in length, play important
roles in the development and progression of various cancers. An increasing number of …

Aberrant expression of UCA1 in gastric cancer and its clinical significance

Q Zheng, F Wu, WY Dai, DC Zheng, C Zheng… - Clinical and …, 2015 - Springer
Long noncoding RNAs (lncRNAs) have been shown to regulate tumor biology and might be
used for cancer diagnosis, prognosis and potential therapeutic targets. Although up …

[HTML][HTML] Epigenetic regulation by lncRNAs: an overview focused on UCA1 in colorectal cancer

B Neve, N Jonckheere, A Vincent, I Van Seuningen - Cancers, 2018 - mdpi.com
Colorectal cancers have become the second leading cause of cancer-related deaths. In
particular, acquired chemoresistance and metastatic lesions occurring in colorectal cancer …

[HTML][HTML] UCA1 long non-coding RNA: An update on its roles in malignant behavior of cancers

S Ghafouri-Fard, M Taheri - Biomedicine & Pharmacotherapy, 2019 - Elsevier
The lncRNA urothelial carcinoma-associated 1 (UCA1) is a 1.4 kb long transcript which has
been firstly recognized in human bladder cancer cell line. Subsequent studies revealed its …

The functional role of long non-coding RNA UCA1 in human multiple cancers: a review study

NF Hosseini, H Manoochehri, SG Khoei… - Current molecular …, 2021 - ingentaconnect.com
In various cancers, high-grade tumor and poor survival rate in patients with upregulated
lncRNAs UCA1 have been confirmed. Urothelial carcinoma associated 1 (UCA1) is an …

[HTML][HTML] Long non-coding RNA UCA1 indicates an unfavorable prognosis and promotes tumorigenesis via regulating AKT/GSK-3β signaling pathway in …

Y Xu, Y Yao, K Leng, Z Li, W Qin, X Zhong, P Kang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) have been documented to play key roles in a wide range
of pathophysiological processes, including cancer initiation and progression. Recently, the …

UCA 1 promotes cell proliferation and invasion of gastric cancer by targeting CREB 1 sponging to miR‐590‐3p

L Gu, L Lu, D Zhou, Z Liu - Cancer medicine, 2018 - Wiley Online Library
Long noncoding RNA s (lnc RNA s) have emerged as regulators in a variety of biological
processes, including carcinogenesis in human cancer. UCA 1 has been reported to be …

[HTML][HTML] lncRNA UCA1 predicts a poor prognosis and regulates cell proliferation and migration by repressing p21 and SPRY1 expression in GC

X He, J Wang, J Chen, L Han, X Lu, D Miao… - … Therapy-Nucleic Acids, 2019 - cell.com
Dysregulated expression of long non-coding RNAs (lncRNAs) has been reported in many
types of cancers, indicating that it has important regulatory roles in human cancer biology …