Arg389Gly polymorphism of the human β1-adrenergic receptor in patients with nonfatal acute myocardial infarction

C Iwai, H Akita, K Kanazawa, N Shiga… - American heart …, 2003 - Elsevier
BACKGROUND: We sought to investigate the relation between the Arg389Gly
polymorphism in the human β1-adrenergic receptor (ADRB1) gene and acute myocardial …

Association of β‐1 and β‐2 adrenergic receptor gene polymorphisms with myocardial infarction

A Yilmaz, MG Kaya, U Merdanoglu… - Journal of Clinical …, 2009 - Wiley Online Library
Abstract Both β1‐and β2‐adrenergic receptors (β1‐and β2‐AR) have important roles in
heart function mainly in response to catecholamines. Some specific polymorphisms in the β1 …

[HTML][HTML] ADRB2 polymorphisms predict the risk of myocardial infarction and coronary artery disease

DW Wang, M Liu, P Wang, X Zhan, YQ Liu… - Genetics and molecular …, 2015 - SciELO Brasil
Recently, the rs1042713 G> A and rs1042714 C> G polymorphisms in the beta-2 adrenergic
receptor (ADRB2) gene were shown to be related to atherosclerosis diseases. Therefore, we …

T64A polymorphism in β3‐adrenergic receptor gene (ADRB3) and coronary heart disease: a case‐cohort study and meta‐analysis

MH Zafarmand, YT Van Der Schouw… - Journal of internal …, 2008 - Wiley Online Library
Objectives. A missense mutation of the human ADRB3 gene replacing tryptophan with
arginine at codon 64 (Trp64Arg) has been related to obesity, insulin resistance, earlier onset …

β2-adrenergic receptor genotype and survival among patients receiving β-blocker therapy after an acute coronary syndrome

DE Lanfear, PG Jones, S Marsh, S Cresci, HL McLeod… - Jama, 2005 - jamanetwork.com
ContextPrevious data support an association between polymorphisms of the β1-and β2-
adrenergic receptors (ADRB1 and ADRB2) and surrogate end points of response to β …

An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals at risk of coronary events. A WOSCOPS substudy

HL White, A Maqbool, AD McMahon… - European heart …, 2002 - academic.oup.com
Abstract Aims The Glycine389 variant of the beta-1 adrenergic receptor generates markedly
less cAMP when stimulated in vitro than the more prevalent Arginine389 variant and may …

Haplotype analysis of the β2 adrenergic receptor gene and risk of myocardial infarction in humans

RYL Zee, NR Cook, R Reynolds, S Cheng… - Genetics, 2005 - academic.oup.com
Polymorphisms in the β2 adrenergic receptor (ADRB2), in particular G16R, Q27E, and
T164I, have been implicated in the pathogenesis of cardiovascular and metabolic …

Effects of Ile164 Polymorphism of Beta2-Adrenergic Receptor Gene on Coronary Artery Disease

F Piscione, G Iaccarino, G Galasso, E Cipolletta… - Journal of the American …, 2008 - jacc.org
Objectives: This study investigated the relationship between beta2-adrenergic receptor
(B2AR) Ile164 polymorphism and coronary artery disease (CAD). Background: B2ARs are …

Genetic polymorphism of beta-adrenergic receptors and mortality in ischemic heart disease

P Jaillon, T Simon - Therapie, 2007 - europepmc.org
The genetic polymorphism of beta-2 adrenergic receptors (B2AR) could play a major role in
the prognostic of patients with a coronary heart disease. Two recent epidemiological studies …

A common variant in the β2-adrenergic receptor and risk of sudden cardiac death

MC Gavin, C Newton-Cheh, JM Gaziano, NR Cook… - Heart Rhythm, 2011 - Elsevier
BACKGROUND: Homozygosity for a common nonsynonymous single nucleotide
polymorphism (Gln27Glu) in the β2-adrenergic receptor gene (ADRB2) has been …