A Yilmaz, MG Kaya, U Merdanoglu… - Journal of Clinical …, 2009 - Wiley Online Library
Abstract Both β1‐and β2‐adrenergic receptors (β1‐and β2‐AR) have important roles in heart function mainly in response to catecholamines. Some specific polymorphisms in the β1 …
DW Wang, M Liu, P Wang, X Zhan, YQ Liu… - Genetics and molecular …, 2015 - SciELO Brasil
Recently, the rs1042713 G> A and rs1042714 C> G polymorphisms in the beta-2 adrenergic receptor (ADRB2) gene were shown to be related to atherosclerosis diseases. Therefore, we …
MH Zafarmand, YT Van Der Schouw… - Journal of internal …, 2008 - Wiley Online Library
Objectives. A missense mutation of the human ADRB3 gene replacing tryptophan with arginine at codon 64 (Trp64Arg) has been related to obesity, insulin resistance, earlier onset …
DE Lanfear, PG Jones, S Marsh, S Cresci, HL McLeod… - Jama, 2005 - jamanetwork.com
ContextPrevious data support an association between polymorphisms of the β1-and β2- adrenergic receptors (ADRB1 and ADRB2) and surrogate end points of response to β …
HL White, A Maqbool, AD McMahon… - European heart …, 2002 - academic.oup.com
Abstract Aims The Glycine389 variant of the beta-1 adrenergic receptor generates markedly less cAMP when stimulated in vitro than the more prevalent Arginine389 variant and may …
RYL Zee, NR Cook, R Reynolds, S Cheng… - Genetics, 2005 - academic.oup.com
Polymorphisms in the β2 adrenergic receptor (ADRB2), in particular G16R, Q27E, and T164I, have been implicated in the pathogenesis of cardiovascular and metabolic …
F Piscione, G Iaccarino, G Galasso, E Cipolletta… - Journal of the American …, 2008 - jacc.org
Objectives: This study investigated the relationship between beta2-adrenergic receptor (B2AR) Ile164 polymorphism and coronary artery disease (CAD). Background: B2ARs are …
P Jaillon, T Simon - Therapie, 2007 - europepmc.org
The genetic polymorphism of beta-2 adrenergic receptors (B2AR) could play a major role in the prognostic of patients with a coronary heart disease. Two recent epidemiological studies …