Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus
S Chamberland, Y Timofeeva… - Proceedings of the …, 2018 - National Acad Sciences
Neuronal communication relies on action potential discharge, with the frequency and the
temporal precision of action potentials encoding information. Hippocampal mossy fibers …
temporal precision of action potentials encoding information. Hippocampal mossy fibers …
Main determinants of presynaptic Ca2+ dynamics at individual mossy fiber–CA3 pyramidal cell synapses
R Scott, DA Rusakov - Journal of Neuroscience, 2006 - Soc Neuroscience
Synaptic transmission between hippocampal mossy fibers (MFs) and CA3 pyramidal cells
exhibits remarkable use-dependent plasticity. The underlying presynaptic mechanisms …
exhibits remarkable use-dependent plasticity. The underlying presynaptic mechanisms …
Timing and efficacy of Ca2+ channel activation in hippocampal mossy fiber boutons
J Bischofberger, JRP Geiger, P Jonas - Journal of Neuroscience, 2002 - Soc Neuroscience
The presynaptic Ca2+ signal is a key determinant of transmitter release at chemical
synapses. In cortical synaptic terminals, however, little is known about the kinetic properties …
synapses. In cortical synaptic terminals, however, little is known about the kinetic properties …
Action potential initiation and propagation in hippocampal mossy fibre axons
C Schmidt‐Hieber, P Jonas… - The Journal of …, 2008 - Wiley Online Library
Dentate gyrus granule cells transmit action potentials (APs) along their unmyelinated mossy
fibre axons to the CA3 region. Although the initiation and propagation of APs are …
fibre axons to the CA3 region. Although the initiation and propagation of APs are …
Interplay between synchronization of multivesicular release and recruitment of additional release sites support short-term facilitation at hippocampal mossy fiber to …
S Chamberland, A Evstratova, K Tóth - Journal of Neuroscience, 2014 - Soc Neuroscience
Synaptic short-term plasticity is a key regulator of neuronal communication and is controlled
via various mechanisms. A well established property of mossy fiber to CA3 pyramidal cell …
via various mechanisms. A well established property of mossy fiber to CA3 pyramidal cell …
Short-term facilitation at a detonator synapse requires the distinct contribution of multiple types of voltage-gated calcium channels
S Chamberland, A Evstratova, K Tóth - Journal of Neuroscience, 2017 - Soc Neuroscience
Neuronal calcium elevations are shaped by several key parameters, including the
properties, density, and the spatial location of voltage-gated calcium channels (VGCCs) …
properties, density, and the spatial location of voltage-gated calcium channels (VGCCs) …
Glutamate imaging reveals multiple sites of stochastic release in the CA3 giant mossy fiber boutons
One of the most studied central synapses which have provided fundamental insights into
cellular mechanisms of neural connectivity is the “giant” excitatory connection between …
cellular mechanisms of neural connectivity is the “giant” excitatory connection between …
Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network
J Bischofberger, D Engel, M Frotscher, P Jonas - Pflügers Archiv, 2006 - Springer
It is widely accepted that the hippocampus plays a major role in learning and memory. The
mossy fiber synapse between granule cells in the dentate gyrus and pyramidal neurons in …
mossy fiber synapse between granule cells in the dentate gyrus and pyramidal neurons in …
Dynamic control of presynaptic Ca2+ inflow by fast-inactivating K+ channels in hippocampal mossy fiber boutons
JRP Geiger, P Jonas - Neuron, 2000 - cell.com
Abstract Analysis of presynaptic determinants of synaptic strength has been difficult at
cortical synapses, mainly due to the lack of direct access to presynaptic elements. Here we …
cortical synapses, mainly due to the lack of direct access to presynaptic elements. Here we …
Slow‐decaying presynaptic calcium dynamics gate long‐lasting asynchronous release at the hippocampal mossy fiber to CA3 pyramidal cell synapse
S Chamberland, Y Timofeeva, A Evstratova… - Synapse, 2020 - Wiley Online Library
Action potentials trigger two modes of neurotransmitter release, with a fast synchronous
component and a temporally delayed asynchronous release. Asynchronous release …
component and a temporally delayed asynchronous release. Asynchronous release …