Idiopathic Pulmonary Fibrosis (IPF) is a chronic interstitial lung disease which results in end-
stage fibrosis. The pathogenesis is believed to be related to a dysregulation in cross-talk …

Idiopathic pulmonary fibrosis is a prototype of chronic, progressive, and fibrotic lung disease.
Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is …

In the past several years, significant progress in many aspects of pulmonary fibrosis
research has been made. Among them, the finding that a variety of cytokines play important …

Pulmonary fibrosis is a devastating disorder that is resistant to treatment. Patients with
idiopathic pulmonary fibrosis (IPF) have a median survival of 4 to 5 yr after onset of …

Pulmonary fibrosis is characterized by an increase in lung matrix and alterations in the
numbers and spatial relationships of lung parenchymal cells. The increase in matrix results …

In the lungs, fibrosis is a growing clinical problem that results in shortness of breath and can
end up in respiratory failure. Even though the main fibrotic disease affecting the lung is …

Fibrogenic lung reactions occur as a common phenotype shared among disorders of
heterogeneous etiologies. Even with a common etiology, the extent and pattern of fibrosis …

Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of
unknown etiology and with an unfavorable outcome, leading ultimately to death due to …

This perspective highlights some evidence that has hitherto been neglected, especially
because it may not have been sufficiently explicated in the clinical respiratory medicine …

Oxidative stress has been linked to various disease states as well as physiological aging.
The lungs are uniquely exposed to a highly oxidizing environment and have evolved several …