Characterization of the inflammatory response to severe COVID-19 illness

OJ McElvaney, NL McEvoy, OF McElvaney… - American journal of …, 2020 - atsjournals.org
Rationale: Coronavirus disease (COVID-19) is a global threat to health. Its inflammatory
characteristics are incompletely understood. Objectives: To define the cytokine profile of …

[HTML][HTML] Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis

JG Wilson, LJ Simpson, AM Ferreira, A Rustagi… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Elevated levels of inflammatory cytokines have been associated with poor
outcomes among COVID-19 patients. It is unknown, however, how these levels compare …

[HTML][HTML] Immune characteristics distinguish patients with severe disease associated with SARS-CoV-2

X Li, Y Liu, J Li, L Sun, J Yang, F Xu, J Zhou… - Immunologic …, 2020 - Springer
This single-center, retrospective study aimed to explore the immune characteristics of
COVID-19 and biomarkers to predict the severity of this disease. Patients infected with SARS …

[HTML][HTML] Elevated levels of neutrophil activated proteins, alpha-defensins (DEFA1), calprotectin (S100A8/A9) and myeloperoxidase (MPO) are associated with disease …

S Shrivastava, S Chelluboina, P Jedge… - Frontiers in Cellular …, 2021 - frontiersin.org
Understanding of the basis for severity and fatal outcome of SARS-CoV-2 infection is of
paramount importance for developing therapeutic options and identification of prognostic …

[HTML][HTML] Evaluating the effects of circulating inflammatory proteins as drivers and therapeutic targets for severe COVID-19

A Baranova, J Luo, L Fu, G Yao, F Zhang - Frontiers in Immunology, 2024 - frontiersin.org
Objective The relationships between circulating inflammatory proteins and COVID-19 have
been observed in previous cohorts. However, it is not unclear which circulating inflammatory …

[HTML][HTML] Cytokine signature and COVID-19 prediction models in the two waves of pandemics

S Cabaro, V D'Esposito, T Di Matola, S Sale… - Scientific Reports, 2021 - nature.com
In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed.
Here, we have investigated whether common patterns of cytokines could be detected in …

[HTML][HTML] Association between the expression of toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity

W Alturaiki, H Alkadi, S Alamri, ME Awadalla, A Alfaez… - Heliyon, 2023 - cell.com
The recent identification of the involvement of the immune system response in the severity
and mortality of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection highlights …

[HTML][HTML] From cell to symptoms: The role of SARS-CoV-2 cytopathic effects in the pathogenesis of COVID-19 and long COVID

P Gonzalez-Garcia, O Fiorillo Moreno… - International Journal of …, 2023 - mdpi.com
Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection triggers various
events from molecular to tissue level, which in turn is given by the intrinsic characteristics of …

'Composite index'in COVID-19 related 'Dragon'Pandemic: Novel approach to predict outcome

S Patil, G Gondhali, V Bhalerao - World Journal of Advanced …, 2023 - zealjournals.com
COVID-19 related 'Dragon pandemic'caused significant mortality and its lingering effects as
long covid with huge impact on morbidity and quality of life. As pandemic has waned off, still …

[HTML][HTML] An analysis of hematological, coagulation and biochemical markers in COVID-19 disease and their association with clinical severity and mortality: an Indian …

M Pujani, S Raychaudhuri, M Singh… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Background: The “cytokine storm”(CS) in COVID-19 leads to the worst stage of illness which
can be controlled only with timely intervention. There is an urgent need to identify laboratory …