Plasma proteome fingerprints reveal distinctiveness and clinical outcome of SARS-CoV-2 infection

W Bauer, M Weber, E Diehl-Wiesenecker, N Galtung… - Viruses, 2021 - mdpi.com
Background: We evaluated how plasma proteomic signatures in patients with suspected
COVID-19 can unravel the pathophysiology, and determine kinetics and clinical outcome of …

Longitudinal plasma proteomics analysis reveals novel candidate biomarkers in acute COVID-19

Y Mohammed, DR Goodlett, MP Cheng… - Journal of proteome …, 2022 - ACS Publications
The host response to COVID-19 pathophysiology over the first few days of infection remains
largely unclear, especially the mechanisms in the blood compartment. We report on a …

Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes

A Viode, KK Smolen, P van Zalm, D Stevenson… - Science …, 2024 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by highly heterogeneous manifestations ranging from asymptomatic cases to death for still …

Plasma proteomics unveil novel immune signatures and biomarkers upon SARS-CoV-2 infection

V Urbiola-Salvador, S Lima de Souza… - International Journal of …, 2023 - mdpi.com
Several elements have an impact on COVID-19, including comorbidities, age and sex. To
determine the protein profile changes in peripheral blood caused by a SARS-CoV-2 …

In-depth blood proteome profiling analysis revealed distinct functional characteristics of plasma proteins between severe and non-severe COVID-19 patients

J Park, H Kim, SY Kim, Y Kim, JS Lee, K Dan… - Scientific reports, 2020 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over forty
million patients worldwide. Although most coronavirus disease 2019 (COVID-19) patients …

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia

LM Palma Medina, H Babačić, M Dzidic, Å Parke… - Respiratory …, 2023 - Springer
Background COVID-19 remains a major public health challenge, requiring the development
of tools to improve diagnosis and inform therapeutic decisions. As dysregulated …

Mapping the serum proteome of COVID-19 patients; guidance for severity assessment

E Nuñez, I Orera, L Carmona-Rodríguez, JR Paño… - Biomedicines, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), whose outbreak in 2019 led to an ongoing pandemic with …

Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications

MAY Al-Nesf, HB Abdesselem, I Bensmail… - Nature …, 2022 - nature.com
COVID-19 complications still present a huge burden on healthcare systems and warrant
predictive risk models to triage patients and inform early intervention. Here, we profile 893 …

Plasma proteomics identify potential severity biomarkers from COVID‐19 associated network

AT Sahin, A Yurtseven, S Dadmand… - PROTEOMICS …, 2023 - Wiley Online Library
Abstract Purpose Coronavirus disease 2019 (COVID‐19) continues to threaten public health
globally. Severe acute respiratory coronavirus type 2 (SARS‐CoV‐2) infection‐dependent …

Validating a proteomic signature of severe COVID-19

CV Cosgriff, TA Miano, D Mathew… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: COVID-19 is a heterogenous disease. Biomarker-based approaches may
identify patients at risk for severe disease, who may be more likely to benefit from specific …