Only in recent years, thanks to a precision medicine-based approach, have treatments
tailored to the sex of each patient emerged in clinical trials. In this regard, both striated …

Skeletal muscle health is a strong predictor of overall health and longevity. Pathologies
affecting skeletal muscle such as cancer cachexia, intensive care unit treatment, muscular …

Sex differences in muscle aging are poorly understood, but could be crucial for the
optimization of sarcopenia-related interventions. To gain insight into potential sex …

Skeletal muscle is a dynamic organ that responds to various stimuli by altering its size,
strength, and composition. Maintenance of skeletal muscle mass and strength is critical for …

Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …

With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

As our population grows older, age-related pathologies are becoming more prevalent.
Deterioration of skeletal muscle and the immune system manifests as sarcopenia and …

Background Aging leads to decreased skeletal muscle function in mammals and is
associated with a progressive loss of muscle mass, quality and strength. Age-related muscle …

Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …

Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …