Proteomic profiling and artificial intelligence for hepatocellular carcinoma translational medicine

NT Moldogazieva, IM Mokhosoev, SP Zavadskiy… - Biomedicines, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver with high
morbidity and mortality rates worldwide. Since 1963, when alpha-fetoprotein (AFP) was …

The role of artificial intelligence in the detection and implementation of biomarkers for hepatocellular carcinoma: outlook and opportunities

A Mansur, A Vrionis, JP Charles, K Hancel… - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer is a major health problem worldwide, and its early detection
and management are imperative for improving patient outcomes. Biomarkers have great …

Future of molecular profiling of human hepatocellular carcinoma

S Roessler, A Budhu, XW Wang - Future oncology, 2007 - Taylor & Francis
Hepatocellular carcinoma (HCC) is a fatal disease occurring worldwide and developing
mainly in chronic liver diseased patients. Despite routine screening of individuals at high …

[HTML][HTML] Artificial intelligence in the detection, characterisation and prediction of hepatocellular carcinoma: a narrative review

M Kawka, A Dawidziuk, LR Jiao… - Translational …, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a significant cause of morbidity and mortality worldwide.
Despite significant advancements in detection and treatment of HCC, its management …

Integrated proteomics and bioinformatics to identify potential prognostic biomarkers in hepatocellular carcinoma

Q Zhang, Z Xiao, S Sun, K Wang, J Qian… - Cancer Management …, 2021 - Taylor & Francis
Background Liver hepatocellular carcinoma (HCC) is the third most common cause of death
by cancer and has a high mortality world-widely. Approximately 75–85% of primary liver …

Proteomic expression signature distinguishes cancerous and nonmalignant tissues in hepatocellular carcinoma

NP Lee, L Chen, MC Lin, FH Tsang… - Journal of proteome …, 2009 - ACS Publications
Hepatocellular carcinoma (HCC) is an aggressive liver cancer but clinically validated
biomarkers that can predict natural history of malignant progression are lacking. The present …

Identification of platform-independent diagnostic biomarker panel for hepatocellular carcinoma using large-scale transcriptomics data

H Kaur, A Dhall, R Kumar, GPS Raghava - Frontiers in genetics, 2020 - frontiersin.org
The high mortality rate of hepatocellular carcinoma (HCC) is primarily due to its late
diagnosis. In the past, numerous attempts have been made to design genetic biomarkers for …

[HTML][HTML] Quantitative proteomic profiling of hepatocellular carcinoma at different serum alpha-fetoprotein level

X Wei, R Su, M Yang, B Pan, J Lu, H Lin, W Shu… - Translational …, 2022 - Elsevier
Purpose Hepatocellular carcinoma (HCC) is characterized by a poor long-term prognosis
and high mortality rate. Serum alpha-fetoprotein (AFP) levels show great prognostic value in …

Predictive biomarkers for systemic therapy of hepatocellular carcinoma

NT Moldogazieva, SP Zavadskiy… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Hepatocellular carcinoma (HCC) is the most common primary liver cancer and
the third cancer-related cause of death worldwide. In recent years, several systemic therapy …

Genomic and proteomic biomarkers for diagnosis and prognosis of hepatocellular carcinoma

NPY Lee, ST Cheung, RTP Poon, ST Fan… - Biomarkers in …, 2007 - Taylor & Francis
Hepatocellular carcinoma is one of the most deadly liver malignancies found worldwide,
with hepatitis virus infection being the prominent risk factor for this lesion. Patients with …