[HTML][HTML] Parallels in sepsis and COVID-19 conditions: implications for managing severe COVID-19

CO Olwal, NN Nganyewo, K Tapela… - Frontiers in …, 2021 - frontiersin.org
Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to
infection. Sepsis is a global burden killing~ 11 million persons annually. In December 2019 …

[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …

Therapeutic approaches for COVID-19 based on the dynamics of interferon-mediated immune responses

P Mosaddeghi, M Negahdaripour, Z Dehghani… - 2020 - preprints.org
As the outbreak of COVID-19 has accelerated, an urgent need for finding strategies to
combat the virus is growing. Thus, gaining more knowledge on the pathogenicity …

[PDF][PDF] A dynamic immune response shapes COVID-19 progression

EZ Ong, YFZ Chan, WY Leong, NMY Lee… - Cell host & …, 2020 - cell.com
The inflammatory response to SARS-coronavirus-2 (SARS-CoV-2) infection is thought to
underpin COVID-19 pathogenesis. We conducted daily transcriptomic profiling of three …

Macrophage responses associated with COVID-19: A pharmacological perspective

GW Booz, R Altara, AH Eid, Z Wehbe, S Fares… - European Journal of …, 2020 - Elsevier
COVID-19 has caused worldwide death and economic destruction. The pandemic is the
result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has …

Cell-mediated immune responses to COVID-19 infection

A Guihot, E Litvinova, B Autran, P Debre… - Frontiers in …, 2020 - frontiersin.org
An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV),
subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City …

Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …

Cell death in coronavirus infections: Uncovering its role during COVID-19

A Paolini, R Borella, S De Biasi, A Neroni, M Mattioli… - Cells, 2021 - mdpi.com
Cell death mechanisms are crucial to maintain an appropriate environment for the
functionality of healthy cells. However, during viral infections, dysregulation of these …

[PDF][PDF] Virus-host interactome and proteomic survey reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

J Li, M Guo, X Tian, X Wang, X Yang, P Wu, C Liu… - Med, 2021 - cell.com
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global public health …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …