OBJECTIVE: In human pathology, SARS-CoV-2 utilizes multiple molecular pathways to
determine structural and biochemical changes within the different organs and cell types. The …

Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with
hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular …

The SARS-CoV-2 virus is a pathogen causing the coronavirus infection that culminated in a
worldwide pandemic in 2020. It belongs to β-coronaviruses and has high genetic similarity …

Background: The Coronavirus Disease 2019 (COVID-19) is becoming the major health
issue in recent human history with thousands of deaths and millions of cases worldwide …

Background COVID-19 pandemic has led to overloading of health systems all over the
world. For reliable risk stratification, knowledge on factors predisposing to SARS-CoV-2 …

In light of the outbreak of the 2019 novel coronavirus disease (COVID-19), the international
scientific community has joined forces to develop effective treatment strategies. The …

SARS-CoV-2 impairs the renin-angiotensin-aledosterone system via binding ACE2 enzyme.
ACE2 plays a key role in the biosynthesis of angiotensin (1-7), catalyzing the conversion of …

The angiotensin-converting enzyme 2 (ACE2) is the host functional receptor for the new
virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different …

Abstract In December 2019, Wuhan city in the Hubei province of China reported for the first
time a cluster of patients infected with a novel coronavirus, since then there has been an …

Abstract Angiotensin-converting enzyme 2 (ACE2) has been recognized as a potential entry
receptor for SARS-CoV-2 infection. Binding of SARS-CoV-2 to ACE2 allows engagement …