Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective …

M St John Sutton, MA Pfeffer, T Plappert, JL Rouleau… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Left ventricular enlargement after myocardial infarction increases the
likelihood of an adverse outcome. In an echocardiographic substudy of the Survival and …

Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement …

MA Pfeffer, E Braunwald, LA Moyé… - New England journal …, 1992 - Mass Medical Soc
Background. Left ventricular dilatation and dysfunction after myocardial infarction are major
predictors of death. In experimental and clinical studies, long-term therapy with the …

Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction

SD Solomon, H Skali, NS Anavekar, M Bourgoun… - Circulation, 2005 - Am Heart Assoc
Background—Angiotensin-converting enzyme (ACE) inhibitors have been shown to
attenuate left ventricular (LV) enlargement in association with reducing mortality after …

Cardiovascular death and left ventricular remodeling two years after myocardial infarction: baseline predictors and impact of long-term use of captopril: information …

MSJ Sutton, MA Pfeffer, L Moye, T Plappert… - Circulation, 1997 - Am Heart Assoc
Background We quantified cardiovascular death and/or left ventricular (LV) dilatation in
patients from the SAVE trial to determine whether dilatation continued beyond 1 year …

The importance of defining left ventricular area at risk in vivo during acute myocardial infarction: an experimental evaluation with myocardial contrast two-dimensional …

S Kaul, W Glasheen, TD Ruddy, NG Pandian… - Circulation, 1987 - Am Heart Assoc
Because the left ventricular" area at risk" is the most important determinant of ultimate infarct
size, it would be useful to know the size of the area at risk during acute myocardial infarction …

Ventricular enlargement and reduced survival after myocardial infarction.

MA Pfeffer, JM Pfeffer - Circulation, 1987 - europepmc.org
Increased ventricular volume is one of the most powerful predictors of reduced survival in
patients with heart disease. Despite its well-documented prognostic significance, the …

The prognostic value of predischarge quantitative two-dimensional echocardiographic measurements and the effects of early lisinopril treatment on left ventricular …

Gruppo Italiano per lo Studio della … - European heart …, 1996 - academic.oup.com
Background Left ventricular dilatation and a low ejection fraction after acute myocardial
infarction are independent indicators of a poor prognosis. ACE inhibitors have been shown …

Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion.

RG McKay, MA Pfeffer, RC Pasternak, JE Markis… - Circulation, 1986 - Am Heart Assoc
Dilatation of infarcted segments (infarct expansion) may occur during recovery from
myocardial infarction, but the fate of noninfarcted segments is uncertain. Accordingly, left …

Left ventricular remodeling in the year after first anterior myocardial infarction: a quantitative analysis of contractile segment lengths and ventricular shape

GF Mitchell, GA Lamas, DE Vaughan… - Journal of the American …, 1992 - Elsevier
Infarct expansion after myocardial infarction results in early ventricular enlargement and
distortion of ventricular geometry. To characterize the components of late volume …

Left ventricular remodeling after acute myocardial infarction: clinical course and beneficial effects of angiotensin-converting enzyme inhibition

GA Lamas, MA Pfeffer - American heart journal, 1991 - Elsevier
LV enlargement is an important determinant of survival after AMI. Pathyphosiologic
mechanisms leading to LV dilatation after an AMI include early thinning and stretching of the …