Here, we show that a nucleosome obstructing transcription from the IFN-β promoter slides in
vivo in response to virus infection, thus exposing the previously masked TATA box and the …

One hallmark of ATP-dependent remodeling complexes is the ability to make nucleosomal
DNA accessible to regulatory factors. We have compared two prominent human ATP …

The Drosophila nucleosome remodeling factor (NURF) is an imitation switch (ISWI)‐
containing chromatin remodeling complex that can catalyze nucleosome repositioning at …

The chromatin landscape and promoter architecture are dominated by the interplay of
nucleosome and transcription factor (TF) binding to crucial DNA sequence elements …

Here, we show that the IFN-β enhanceosome activates transcription by directing the ordered
recruitment of chromatin modifying and general transcription factors to the IFN-β promoter …

Chromatin-remodeling complexes regulate access to nucleosomal DNA by mobilizing
nucleosomes in an ATP-dependent manner. In this study, we find that chromatin remodeling …

Chromatin-remodeling enzymes can overcome strong histone-DNA interactions within the
nucleosome to regulate access of DNA-binding factors to the genetic code. By unzipping …

Regulation of gene expression requires dynamic changes in chromatin, but the nature of
these changes is not well understood. Here, we show that progesterone treatment of …

The ATP-dependent chromatin remodeling complex SWI/SNF regulates transcription and
has been implicated in promoter nucleosome eviction. Efficient nucleosome disassembly by …

To investigate the mechanism of SWI/SNF action, we have analyzed the pathway by which
SWI/SNF stimulates formation of transcription factor-bound nucleosome core complexes. We …