Tendon injuries: Basic science and new repair proposals

F Wu, M Nerlich, D Docheva - EFORT open reviews, 2017 - eor.bioscientifica.com
Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons
become more prone to degeneration followed by injuries. Tendon repair often requires …

[HTML][HTML] Biologics for tendon repair

D Docheva, SA Müller, M Majewski… - Advanced drug delivery …, 2015 - Elsevier
Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

Mesenchymal stem cells empowering tendon regenerative therapies

R Costa-Almeida, I Calejo, ME Gomes - International journal of molecular …, 2019 - mdpi.com
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …

Stem cell technology for tendon regeneration: current status, challenges, and future research directions

PPY Lui - Stem cells and cloning: advances and applications, 2015 - Taylor & Francis
Tendon injuries are a common cause of physical disability. They present a clinical challenge
to orthopedic surgeons because injured tendons respond poorly to current treatments …

[HTML][HTML] Rescue plan for Achilles: Therapeutics steering the fate and functions of stem cells in tendon wound healing

M Schneider, P Angele, TAH Järvinen… - Advanced drug delivery …, 2018 - Elsevier
Due to the increasing age of our society and a rise in engagement of young people in
extreme and/or competitive sports, both tendinopathies and tendon ruptures present a …

Tendon stem progenitor cells: Understanding the biology to inform therapeutic strategies for tendon repair

B Walia, AH Huang - Journal of Orthopaedic Research®, 2019 - Wiley Online Library
Tendon and ligament injuries are a leading cause of healthcare visits with significant impact
in terms of economic cost and reduced quality of life. To date, reparative strategies remain …

Tendon basic science: Development, repair, regeneration, and healing

N Andarawis‐Puri, EL Flatow… - Journal of Orthopaedic …, 2015 - Wiley Online Library
Tendinopathy and tendon rupture are common and disabling musculoskeletal conditions.
Despite the prevalence of these injuries, a limited number of investigators are conducting …

Stem cells for tendon tissue engineering and regeneration

Z Yin, X Chen, J Chen, HW Ouyang - Expert opinion on biological …, 2010 - Taylor & Francis
Importance of the field: Tendon injuries are common especially in sports activities, but
tendon is a unique connective tissue with poor self-repair capability. With advances in stem …

Basic research on tendon repair: Strategies, evaluation, and development

ZJ Li, QQ Yang, YL Zhou - Frontiers in medicine, 2021 - frontiersin.org
Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided
into two types, chronic and acute. Each type of injury or degeneration can cause substantial …

Tendon biomechanics and mechanobiology—a minireview of basic concepts and recent advancements

JHC Wang, Q Guo, B Li - Journal of hand therapy, 2012 - Elsevier
Due to their unique hierarchical structure and composition, tendons possess characteristic
biomechanical properties, including high mechanical strength and viscoelasticity, which …