Background Evidence suggests the role of an inflammatory storm in COVID-19
complications. Colchicine is an orally administered, anti-inflammatory medication beneficial …

Introduction Colchicine may inhibit inflammasome signaling and reduce proinflammatory
cytokines, a purported mechanism of COVID-19 pneumonia. The aim of this systematic …

Background Colchicine has been used an effective anti-inflammatory drug to treat gout
diseases. Owing to its pharmacodynamic of inhibiting interleukins, it has been repurposed to …

Background Evidence suggests a role for excessive inflammation in COVID-19
complications. Colchicine is an oral anti-inflammatory medication beneficial in gout …

Objectives Effective treatments for coronavirus disease 2019 (COVID-19) are urgently
needed. We hypothesized that colchicine, by counteracting proinflammatory pathways …

Background. Colchicine has been used in conditions such as periodic febrile illness, acute
pericarditis, and gouty arthritis, all having a common hyperinflammatory response as seen in …

Background Colchicine has been proposed as a treatment for COVID-19 based on its anti-
inflammatory actions. We aimed to evaluate the efficacy and safety of colchicine in patients …

The repurposing of colchicine for the treatment of COVID-19 was suggested based in its
immunomodulatory, anti-inflammatory, and anti-viral properties. We performed a single …

Objective To evaluate whether the addition of colchicine to standard treatment for COVID-19
results in better outcomes. Design We present the results of a randomised, double-blinded …

Currently, there is no widely acceptable and proven effective treatment for coronavirus
disease 2019 (COVID‐19). Colchicine has been shown to offer a benefit in reducing the …