[HTML][HTML] Mirna expression profiles identify drivers in colorectal and pancreatic cancers

A Piepoli, F Tavano, M Copetti, T Mazza, O Palumbo… - PloS one, 2012 - journals.plos.org
Background and Aim Altered expression of microRNAs (miRNAs) hallmarks many cancer
types. The study of the associations of miRNA expression profile and cancer phenotype …

[HTML][HTML] Serum miR-1290 and miR-1246 as potential diagnostic biomarkers of human pancreatic cancer

J Wei, L Yang, Y Wu, J Xu - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Background: Pancreatic cancer (PC) is a highly malignant tumor with no effective early
diagnostic biomarkers. This study was performed to screen and identify serum microRNAs …

[HTML][HTML] Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma

S Debernardi, NJ Massat, TP Radon… - American journal of …, 2015 - ncbi.nlm.nih.gov
Currently, the majority of patients diagnosed with pancreatic ductal adenocarcinoma (PDAC)
present with locally invasive and/or metastatic disease, resulting in five-year survival of less …

The role of microRNAs in the pathophysiology of adrenal tumors

N Hassan, JT Zhao, SB Sidhu - Molecular and cellular endocrinology, 2017 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression in a
sequence-specific manner. Due to its association with an assortment of diseases, miRNAs …

[HTML][HTML] Clinical significance of circulating miR-1273g-3p and miR-122-5p in pancreatic cancer

T Mazza, D Gioffreda, A Fontana, T Biagini… - Frontiers in …, 2020 - frontiersin.org
The burden of pancreatic cancer (PanC) requires innovation in the current diagnostic
approach. This study aimed to uncover new circulating microRNAs (miRNAs) that would …

[HTML][HTML] Analysis of deregulated microRNAs and their target genes in gastric cancer

S Juzėnas, V Saltenienė, J Kupcinskas, A Link… - PloS one, 2015 - journals.plos.org
Background MicroRNAs (miRNAs) are widely studied non-coding RNAs that modulate gene
expression. MiRNAs are deregulated in different tumors including gastric cancer (GC) and …

MicroRNAs in body fluids—the mix of hormones and biomarkers

MA Cortez, C Bueso-Ramos, J Ferdin… - Nature reviews Clinical …, 2011 - nature.com
Since the discovery of microRNAs (miRNAs), the study of these small noncoding RNAs has
steadily increased and more than 10,000 papers have already been published. The great …

Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression

AE Frampton, L Castellano, T Colombo, E Giovannetti… - The Lancet, 2015 - thelancet.com
Background MicroRNAs (miRNAs) are small non-coding RNAs involved in the post-
transcriptional regulation of mRNAs and are aberrantly expressed in cancer with important …

[HTML][HTML] MicroRNA in pancreatic cancer: from biology to therapeutic potential

M Rawat, K Kadian, Y Gupta, A Kumar, PSG Chain… - Genes, 2019 - mdpi.com
Pancreatic cancer is one of the most aggressive malignancies, accounting for more than
45,750 deaths annually in the US alone. The aggressive nature and late diagnosis of …

[HTML][HTML] Novel circulating miRNA signatures for early detection of pancreatic neoplasia

E Vila-Navarro, S Duran-Sanchon… - Clinical and …, 2019 - journals.lww.com
OBJECTIVES: Pancreatic ductal adenocarcinoma (PDAC) presents the lowest survival rate
of all cancers because only 6% of patients reach five-year survival. Alterations in the …